Question

1)Cortisol stimulates gluconeogenesis through which of the following mechanisms?

a-Phosphorylating hormone sensitive lipase

b-Decreasing levels of fructose 2, 6 biphosphate

c-Activatingphosphofructokinase-1

d-Increasing levels of PEPCK (phosphoenol carboxykinase)

2)When glucagon is elevated it increases gluconeogenesis through which of the following mechanisms?

a-Binding a receptor tyrosine kinase and initiation of MAPKKK cascade

b-Decrease cytosolic levels of cAMP

c-Binding to a nuclear reactor and initiating gene transcription

d-Activating protein kinase A

3)In a patient with hyperthyroidism, which of the following contributes to heat intolerance?

a-Decreased fat mobilization

b-ATP-independent heat generation within mitochondria

c-Decreased transcription of the uncoupling protein within mitochondria

d-Increased storage of iodine