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Biology
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11 Dec 2019

This large and complex general transcription factor has a DNA helicase activity that exposes the template for RNA polymerase II transcription. It also has a kinase activity that phosphorylates the C-terminal domain of the polymerase on Ser5 leading to promoter clearance. It is...

a) TFIIB

b) TFIID

c) TFIIE

d) TFIIF

e) TFIIH

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Casey DurganLv2
13 Dec 2019
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Related questions

TFIIH plays 2 separate roles in the initiation of transcription. What are they? (Choose 2 answers, 1/2 mark each)

Select one or more:

a. cdk7, a component of TFIIH, phosphorylates Ser5 of the CTD of RNA polymerase II.

b. it is involved in 3' end cleavage.

c. It phosphorylates Ser2 of the CTD of RNA polymerase II.

d. helicases in the complex unwind DNA in the promoter

e. TFIIH is a sequence specific transcription factor.

Which of the following transcription factor complexes separates the two strands of DNA template to form the open complex?A) TFIIA B) TFIIB C) TFIID D) TFIIE E) TFIIHWhich of the following transcription factor complexes is the first to bind to a eukaryotic promoter?A) TFIIA B) TFIIB C) TFIID D) TFIIE E) TFIIHDescribe the advantages for an organisms to contain introns in its gene?

9. The nucleotide on the DNA template that marks the starting point for RNA synthesis is called

a. 0 (zero point)

b. +1

c. -1

d. Start codon

e. TATA

10. Which bacterial RNA polymerase synthesizes tRNA?

a. RNA polymerase I

b. RNA polymerase II

c. RNA polymerase III

d. Core enzyme

e. Promoter

11. What general transcription factor has enzymatic activity?

a. Operator

b. TFIIH

c. eIF2

d. RNAP II

e. CTD

12. What enzyme activity/activities is/are known to be associated with the transcription factor in the previous question?

a. protein kinase and a DNA helicase

b. protein phosphatase

c. ribozyme

d. synthesis of RNA

e. a and c

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