The following is a list of hereditary metabolic defects involvingloss of single enzymes of catabolism, and a second list of possibleconsequences. Match each enzyme with its most likely (only one)consequence from the list.
DEFECTS:
a. lack of phosphoglucomutase
b. lack of triose phosphate isomerase
c. lack of phosphofructokinase
d. lack of glycogen phosphorylase kinase
e. lack of phosphorylase a phosphatase
f. lack of isocitrate dehydrogenase
g. lack of pyruvate dehydrogenase
CONSEQUENCES:
1. Inability to use glycogen as an energy source, with no effect onability to use galactose
2. lethal; prevents use of carbohydrates for ATP production
3. impaired ability to obtain energy from carbohydrates
4. Lethal; prevents complete oxidation of all fuel molecules
5. A lower than normal steady state level of glycogen
6. Inability to use glycogen or galactose as an energy source
7.Inability to obtain energy from carbohydrates, and impairedability to obtain energy from amino acids
Please explain the answers in a thorough manner.
The following is a list of hereditary metabolic defects involvingloss of single enzymes of catabolism, and a second list of possibleconsequences. Match each enzyme with its most likely (only one)consequence from the list.
DEFECTS:
a. lack of phosphoglucomutase
b. lack of triose phosphate isomerase
c. lack of phosphofructokinase
d. lack of glycogen phosphorylase kinase
e. lack of phosphorylase a phosphatase
f. lack of isocitrate dehydrogenase
g. lack of pyruvate dehydrogenase
CONSEQUENCES:
1. Inability to use glycogen as an energy source, with no effect onability to use galactose
2. lethal; prevents use of carbohydrates for ATP production
3. impaired ability to obtain energy from carbohydrates
4. Lethal; prevents complete oxidation of all fuel molecules
5. A lower than normal steady state level of glycogen
6. Inability to use glycogen or galactose as an energy source
7.Inability to obtain energy from carbohydrates, and impairedability to obtain energy from amino acids
Please explain the answers in a thorough manner.