3
answers
0
watching
122
views
9 Jan 2018
In the early mouse embryo, the immediate environment of thesomite comprises multiple tissues secreting different signallingmolecules that pattern the somite.
a) Which of these neighbouring embryological structures secretesSonic hedgehog (Shh)?
b) Outline the Shh signal transduction pathway.
c) Describe the experiments in mice that showed that Shh isessential for the activation of myf5transcription in the earlysomite.
d) In a somite cell, how does the myf5 genomic locus integratethe cell signalling in its local environment to regulatetranscription?
In the early mouse embryo, the immediate environment of thesomite comprises multiple tissues secreting different signallingmolecules that pattern the somite.
a) Which of these neighbouring embryological structures secretesSonic hedgehog (Shh)?
b) Outline the Shh signal transduction pathway.
c) Describe the experiments in mice that showed that Shh isessential for the activation of myf5transcription in the earlysomite.
d) In a somite cell, how does the myf5 genomic locus integratethe cell signalling in its local environment to regulatetranscription?
teacherrecoLv10
23 Jul 2023
gloryolalere280Lv10
19 Nov 2022
Already have an account? Log in
Bunny GreenfelderLv2
11 Jan 2018
Already have an account? Log in
