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9 Jan 2018

In a eukaryotic cell, proteins are synthesized, and pass through a series of specialized organelles before reaching their target. Describe how a trans-membrane protein would be synthesized, processed and ultimately become a part of the plasma membrane of the cell.

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Patrina Schowalter
Patrina SchowalterLv2
12 Jan 2018
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Related questions

Which type of membrane-bound organelle would be abundant in a eukaryotic cell that is specialized in the secretion of a protein hormone? 3 pts

Which type of membrane-bound organelle would be abundant in a eukaryotic cell that is specialized in the storage of triglycerides?

Describe the functions of those organelles in your answers.

1 What advantages do organelles provide to eukaryotic cells? Arethey necessarily required or simply an artefact of the evolutionaryhistory of eukaryotes? Why, for example, would eukaryotic cellsrequire a membrane-bound nucleus when prokaryotes seem to replicateefficiently without one?

2. What are the 3 main intracellular transport mechanisms forproteins? How does cell topology influence the particularmechanisms needed to transport a protein among organellesintracellularly?

3. Here’s a chicken and egg question… how are transmembraneproteins added to membranes in newly synthesized organelles ifthere are no translocater proteins already present to directthem?

29 Most proteins destined to enter the endoplasmic reticulum _________.

(a) are transported across the membrane after their synthesis is complete.

(b) are synthesized on free ribosomes in the cytosol.

(c) begin to cross the membrane while still being synthesized.

(d) are keep binding to Signal recognition particle (SRP) while they are translated.

30 Which of the following choices reflects the appropriate order of locations through which a protein destined for the plasma membrane travels?

(a) lysosome → endosome → plasma membrane

(b) ER → lysosome → plasma membrane

(c) Golgi → lysosome → plasma membrane

(d) ER → Golgi → plasma membrane

31 Which of the following statements about vesicle budding from the Golgi is false?

(a) COPII can initiate vesicle budding on Golgi membrane.

(b) Some vesicles budded from Golgi membranes move towards ER.

(c) Once vesicle budding completed, clathrin molecules are released from the vesicle.

(d) Clathrin molecules act at the cytosolic surface of the Golgi membrane.

32 Which of the following statements is false?

(a) The signal sequences on mitochondrial proteins are first bound to translocator on outer membrane after translation.

(b) Most mitochondrial proteins are not imported from the cytosol but are synthesized inside the mitochondria.

(c) Chaperone proteins in the mitochondria facilitate the movement of proteins across the outer and inner mitochondrial membranes.

(d) Mitochondrial proteins cross the membrane in their unfolded state.

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