Question

Match the words (A-E) with the statements below: ( 10 pts)

A. Bohr

B. 2, 3-BPG

C. Carbamate

D. Carbon dioxide

E. Concerted

F. Distal Histidine

G. Heme

H. Hemoglobin

I. Myoglobin

J. Sickle Cell Anemia

This has the ability to protect against carbon monoxide binding to the heme _______________

This is the molecule whose function is to facilitate diffusion of oxygen in muscle cells. ___________

The ability of myoglobin to bind oxygen depends on the presence of a bound prosthetic group called .

The shape of this protein has a sigmoidal curve _______________

As the partial pressure of ___________ increases, the affinity of oxygen binding to hemoglobin decreases. (there can be two answers)

The effect of hydrogen ions and carbon dioxide on the binding of oxygen to hemoglobin is called the _____________ effect

___________ is an allosteric effector that binds to the positive charges on the hemoglobin molecule .

Hemoglobin binding of oxygen is best described as a combination of sequential and ______________ model.

Carbon dioxide forms ______________ groups in proteins by reaction with N-terminal groups.

This condition is a result of a single-point mutation in the β chain of hemoglobin:__________________