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Blood is the transport medium in our bodies. Its special function is to make sure all the tissues receive needed nutrients for survival. It becomes apparent, then, that all components of blood need to be assembled correctly in order for this important transport fluid to function. There is a unique location for the creation of blood that helps to protect the process of hematopoiesis.


1. Where in the adult human body are is/are the blood made/created? Be specific (name specific locations in the body).


2. How does the newly created blood get from its place of origin to the rest of the body? Erythropoiesis, the process of creating red blood cells has its own unique requirements in order to complete the process correctly.


3. What 3 food nutrients (other than the required macronutrients [proteins/carbohydrates]) are
essential for the production of red blood cells? (Hint: all 3 are in the micronutrient category).


4. Highlight all the factors that would serve as a stimulus for erythropoiesis:
a) hemorrhage 

b) insufficient hemoglobin per RBC

c) living at a high altitude

d) breathing pure oxygen

5. What makes blood red? Blood can be either a bright scarlet red or a dark brick red. What creates the difference between the two colors of blood? Can either color indicate an anemia?


6. The process of creating new erythrocytes is under the direction of a hormone, erythropoietin. Where is erythropoietin synthesized and released? What cells are created that will then become mature erythrocytes?

7. Define anemia. Be sure to include the 2 general causes of anemia.              

8. There is a type of anemia that occurs from acute blood loss, i.e. from trauma where the internal environment has been exposed to the outside environment. Name this type of anemia. Explain how this type of anemia would be determined by laboratory analysis.

9. Women in their childbearing years are particularly susceptible to one type of anemia. Name
this type of anemia, its causes and list treatment protocols.

10. Intrinsic factor is protein produced by specific cells (parietal cells) in the lining of the stomach. The elderly tend to have a decreased efficiency of the gastric mucosa (stomach lining) and may end up with another type of anemia, associated with the lack of intrinsic factor. Name this anemia. What is important about intrinsic factor? Why does it contribute to a type of anemia?


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