Serious answers only, thank you.
True or false?
1. Activated Gαs interact with PLC-Ââbeta to produce phosphatidylinositol 3,4,5-Ââtrisphosphate and
diacylglycerol. ( )
2. EGF is an example of hormone. ( )
3. Ras is an example of the heterotrimeric G protein. ( )
4. All members of the G protein coupled receptors have a kinase domain in the cytoplasmic tail domain. (
5. Wnt is an example of the ligand for the RPTK family. ( )
6. GEF activates GPCR receptors. ( )
7. PH domain containing proteins bind to an activated PDGFR. ( )
8. Ligands for GPCR proteins induce dimerization of the receptor. ( )
9. Grb2 is an adaptor protein that binds to a phospho-Ââtyrosine residue of an activated PDGFR through a
SH3 domain. ( )
10. When a cell has a dominant negative Ras mutation, an introduction of a constitutively active
RPTK mutant will allow Ras signaling. ( )
Serious answers only, thank you.
True or false?
1. Activated Gαs interact with PLC-Ââbeta to produce phosphatidylinositol 3,4,5-Ââtrisphosphate and
diacylglycerol. ( )
2. EGF is an example of hormone. ( )
3. Ras is an example of the heterotrimeric G protein. ( )
4. All members of the G protein coupled receptors have a kinase domain in the cytoplasmic tail domain. (
5. Wnt is an example of the ligand for the RPTK family. ( )
6. GEF activates GPCR receptors. ( )
7. PH domain containing proteins bind to an activated PDGFR. ( )
8. Ligands for GPCR proteins induce dimerization of the receptor. ( )
9. Grb2 is an adaptor protein that binds to a phospho-Ââtyrosine residue of an activated PDGFR through a
SH3 domain. ( )
10. When a cell has a dominant negative Ras mutation, an introduction of a constitutively active
RPTK mutant will allow Ras signaling. ( )
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