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11 Dec 2019

Explain Chargaff's rule and why it was helpful in the discovery of the structure of DNA.

Who was Rosalind Franklin and what did she contribute to the search for the DNA structure?

List the physical characteristics of DNA structure.

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Sixta Kovacek
Sixta KovacekLv2
13 Dec 2019
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Related questions

1a. Who was the author of the 1968 book titled “The Double Helix”?

1b. Why was this book so controversial?

1c. What technique was Rosalind Franklin first introduced to in 1938 at Cambridge University?

1d. After completing her degree at Cambridge, to what country did Franklin move to continue her research studies?

1e. Why was Franklin required to stay away from her lab for several weeks?

1f. What research insti tution in England did Franklin move to after completing her work in France?

1g. What research institution in England did Watson and Crick work at?

1h. What was the first major discovery Franklin made about DNA?

1i. What methodology did Watson and Crick use to determine the structure of DNA?

1j. What specific information, other than the helical nature of DNA, did Watson and Crick obtain from the famous “Photo 51”?

1k. Why was it essential that Franklin's paper be published at the same time as Watson and Crick's paper?

1l. From 1953 to 1958, what was the focus of Rosalind Franklin's research?

1m. Which form of DNA discovered by Rosalind Franklin is wetter and found in cells?

1n. True or False: At one point, Watson and Crick were forbidden to continue on with their DNA structure research because of their technical errors.

1o. How many strands of DNA did Rosalind Franklin have to bundle together for her experimental work?

1p. What information about DNA was immediately apparent (to Watson, Crick, and other scientists) when they saw photo 51?

1q. Approximately how many hours did it take to expose one of Franklin's DNA photos?

1r. Without computers, approximately how long could it take to perform the calculations necessary to analyze on of Franklin's photographs?

1s. What two published conclusions (later shown to be incorrect) did Pauling make about DNA structure?

1t. In what year was Watson and Cricks DNA paper published?

1u.How old was Rosalind Franklin when she died?

1v. What disease was responsible for Franklin's death?

1w. What did Franklin regard as her “greatest scientific discovery”?

Why was it impossible for Rosalind Franklin to share the Nobel Prize in Physiology and Medicine awarded to Watson, Crick, and Wilkins in 1962?

Consider the structure of the DNA double helix.

A. You and a friend want to split a double-stranded DNA molecule so you each have half. Is it better to cut the length of DNA in half so each person has a shorter length, or to separate the strands and each take one strand? Explain.

B. In the original 1953 publication describing the discovery of the structure of DNA, Watson and Crick wrote, “It has not escaped our notice that the specific pairings we have postulated immediately suggest a possible copying mechanism for the genetic material.” What did they mean?

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