1. wee1inactivates mitotic cyclin kinase complexes by ___ the kinase portion
dephosphorylating
methylating
acetylating
phosphorylating
2. which protein must be phosphorylated before it is degraded?
cyclin kinase
S phase inhibitor
anaphase inhibitor
cyclin
3. phosphorylation of histones is carried out by ___
MPF
SPF
G1 cyclin kinase
cdc 14
4.
cells are "struck" in __ if lamins are not phosphorylated
G1
metaphase
S
prophase
5.
which protein only interacts with E2F if it is not phosphorylated?
APC
cyclin
lamins
RB (retinoblastoma)
6. what protein phosphorylates RB so S phase can start?
MPF
CaK
G1 cyclin-kinase
SPF
7. -__ is an activator of p21 transcription if there is DNA damage?
E2F
p53
SPF
Myc
8.which protein dephosphorylates histones and any protein that MPF phosphorylated?
cdc 14
SCF
ubiquitin
cdc 25
9. loss of heterozygocity refers to ___
eventually having 2 mutations, one in each allele of a tumor suppressor gene
eventually having 2 copies of a proto-oncogene
always is 2 point mutations
always is 2 pieces of condensed DNA
1. wee1inactivates mitotic cyclin kinase complexes by ___ the kinase portion
| dephosphorylating | |||||||||
| methylating | |||||||||
| acetylating | |||||||||
| phosphorylating 2. which protein must be phosphorylated before it is degraded?
|
3. phosphorylation of histones is carried out by ___
| MPF | |||||||||
| SPF | |||||||||
| G1 cyclin kinase | |||||||||
| cdc 14 4. cells are "struck" in __ if lamins are not phosphorylated
|
5.
which protein only interacts with E2F if it is not phosphorylated?
| APC | |||||||||||||||||||||||||||||||||
| cyclin | |||||||||||||||||||||||||||||||||
| lamins | |||||||||||||||||||||||||||||||||
| RB (retinoblastoma) 6. what protein phosphorylates RB so S phase can start?
|
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