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1) How does both the environment and genetics influence genetic traits such as phenylketonuria?

2) What is the difference between an autosomal dominant and autosomal recessive pattern of inheritance?

3) How does meiosis help predict the probability of producing gametes and inheriting a trait?

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Patrina Schowalter
Patrina SchowalterLv2
5 Apr 2018

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Related questions

7- If G=yellow seeds and g=green seeds, predict the genotypic and phenotypic ratios of a cross between a) two Gg individuals; b) a Gg and a gg. If cross 'a' gives you 2/3 offspring that are yellow and 1/3 that are green, what is the mode of inheritance and what is the genotype of the yellow offspring?

8- For four genes (all autosomal recessive), beginning with a AaBbCcdd x aabbCcDd cross, what is the probability of producing a child in the F1 with the A- bb C- dd phenotype?

9- For three autosomal dominant genes, what is the probability that a cross between two heterozygotes (i.e. AaBbCc x AaBbCc) will produce an offspring with the dominant trait for all genes?

A woman, Melanie, and a man, Allan, who are both carriers for phenylketonuria (a rare autosomal recessive disease) have two daughters, Jessica and Andrea, and two sons, Kyle and James. None of Melanie and Allan's parents, or their siblings, had phenylketonuria. However, both of their sons have the disease.

1) What percentage of Melanie's eggs will carry the phenylketonuria allele?

2) What percentage of Allan’s sperm will carry the phenylketonuria allele?

3) Among Melanie and Allan's four children, how does the observed frequency of affected children compare to the expected frequency? Does the observed result go against the concepts of Mendelian genetics? Explain

A woman, Melanie, and a man, Allan, who are both carriers for phenylketonuria (a rare autosomal recessive disease) have two daughters, Jessica and Andrea, and two sons, Kyle and James. None of Melanie and Allan's parents, or their siblings, had phenylketonuria. However, both of their sons have the disease.
Answer questions 1 to 8 based on this scenario. Please use P to indicate the dominant allele for this condition and p to represent the recessive allele.

1) What are Melanie and Allan's genotypes?

2) Based on the scenario given, what are the most likely genotypes of Melanie's parents and of Allan's parents?

3) What are the genotypes of each of their daughters? What are the genotypes of their sons?

4) What percentage of Melanie's eggs will carry the phenylketonuria allele? What percentage of Allan’s sperm will carry the phenylketonuria allele?

5) Melanie is pregnant and she and Allan have just found out the sex of the fetus is male. What is the probability the fetus is carrying two copies of the recessive phenylketonuria allele, and thus will be affected with the disease?

6) Among Melanie and Allan's four children, how does the observed frequency of affected children compare to the expected frequency? Does the observed result go against the concepts of Mendelian genetics?

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