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1 Jan 2018

Often, people who smoke cigarettes are more susceptible to the effects of toxic chemicals. Explain the basis for this observation from a toxicology perspective

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Beverley Smith
Beverley SmithLv2
2 Jan 2018
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Related questions

More specifically, is nicotine in the concentrations thatsmokers receive when smoking cigarettes toxic? I know that in greatenough concentrations it can be toxic (but then, so can just aboutanything else, including oxygen) and I know that in plants it isused as a defense against insects and can even be used as aninsecticide. However, it has always been my understanding thatnicotine is irrelevant as far as the harmful effects of smokinggo.

I recently had a conversation with another biologist who hadjust quit smoking and had done quite a bit of research on thesubject. He said that nicotine itself is in fact bad for you and,therefore, that tobacco-less alternatives to cigarettes (such aselectronic cigarettes) are still harmful because of thenicotine alone.

Does anyone have any more information on this? Perhaps somereferences? Or, even better, a detailed explanation of the pathwaysinvolved? Again, I stress, not about nicotine's toxicity in generalbut about its harmful effects on vertebrates (preferably human) atthe kinds of concentrations one could expect to ingest whensmoking.

Why are studies on the health effects of smoking among individual who smoke not a concern of environmental epidemiology? Explain the reason why exposure to secondhand cigarette smoke is a concern of this discipline.

One of the major goals of toxicology is to predict risk to humans from exposure to chemicals. This involves the processes of risk assessment and risk management. You are the director of a chemical factory and are planning to bring a new chemical to market. Outline the process by which you would develop a risk assessment/management plan for this chemical to assure it safety to humans from exposure.

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