Question

Please answer all of them thanks

1. Which one of these is not true about conventional chemotherapies? (40pts)

a. High plasma residence time of the drug.

b. Rapid metabolism.

c. Could result in non-specific exposure of other healthy tissues.

2. Which of these is a physiological barrier for drug delivery?

a. Shear stresses exerted on the drug carrier.

b. Phagocytosis.

c. Removal of drug carriers from circulation via vasculature in organs such as liver and kidney.

d. All of the above

3. Doxil, a liposomal doxorubicin formulation, had higher response rate when compared to free drug in Phase 1 clinical trial.

a. True

b. False