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Colchicine is a chemical that disrupts mitosis by inhibiting microtuble polymerization. Describe an experiment that determines the effects of colchicine on meiosis. Include the terms: spindle fiber, synapsis, nondisjunction, and aneuploidy. Draw and label one figure summarizing at least one part of the experiment.

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Tod Thiel
Tod ThielLv2
29 Sep 2019
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Related questions

-Complete the following sentences: metaphase of mitosis, prophase II of meiosis, crossing over, anaphase I of meiosis, variable, random fertilization, identical, random orientation, metaphase I of meiosis, prophase I of meiosis, metaphase II of meiosis, reduction division

Two processes that occur during meiosis produce genetically ____________ cells.

In a process called ____________ , paired homologous chromosomes align randomly at the cell equator. This occurs during this stage of cell division: ____________ .

In a process called ____________ , genetic material is exchanged between homologous chromosomes. This occurs during this stage of cell division: ____________ .

-Complete the following paragraph to describe nondisjunction and the resulting effects on chromosome number.

words: euploidy, primary nondisjunction, nomal, nondisjunction, secondary nondisjunction, homologous chromosomes, abnormal, trisomy, monosomy, sister chromatids, aneuploid

1.During meiosis I, ____________ separate and move towards opposite ends of the poles.

2.During meiosis II, ____________ separate and move towards opposite ends of the poles.

3.During meiosis I, if both members of a homologous pair go into the same daughter cell, ____________ is said to occur and no normal gametes are produced.

4.During meiosis II, if the sister chromatids fail to separate and both daughter chromosomes go into the same gamete, ____________ is said to occur. Half the gametes are aneuploid while the other half are euploid.

5.If an egg that contains 24 chromosomes instead of 23 chromosomes is fertilized by a normal sperm, ____________ is said to have occurred.

6.If an egg that contains 22 chromosomes instead of 23 chromosomes is fertilized by a normal sperm, ____________ is said to have occurred.

What is a genome? What is a genome made of? Describe the bacterial genome. How do bacteria reproduce? What is binary fission? Distinguish between a chromosome and chromatin. Where are chromosomes located in eukaryotic cells? What is the chromosome made of? What is a centromere? What is the centromere's role? What are sister chromatids and how do they arise? Distinguish between somatic cells and germ (gametes) cells. Describe the cell cycle. What are the different phases? What occurs during S phase? What is interphase? How is the cell cycle controlled?

Describe mitosis. What are the phases of mitosis? What occurs in each of the phases of mitosis? What is cytokinesis? How does this differ between plant and animal cells? What is a kinetochore? Where does it form? What is its role? What is the role of microtubules in mitosis? What is a centriole and what is it composed of? What is a centrosome and what is its role in mitosis? What is the metaphase plate and why is this important? What is the mitotic spindle, its role and its makeup? What defines a diploid cell? How many copies of each chromosome is in a diploid cell? What about a haploid cell? Why do the daughter cells of mitosis always have the same complement of chromosomes?

Describe meiosis. What are the phases of meiosis? What occurs in each of the phases of meiosis? Distinguish between meiosis I and meiosis II and describe how each of these processes compare to mitosis. Why do animal cells undergo meiosis? What is a gamete? What is a zygote? What are recombination, crossing-over, and chiasma? When and why does this occur? What is meant by 'homologous pair of chromosomes'? Why don't the daughter cells of meiosis have the same genetic makeup? What controls the segregation of chromosomes into the gametes?

What are genetic characters? What are genetic traits? What is an allele? What is a locus? How many alleles at each locus would a human cell have and why? Distinguish between genotype and phenotype. What is meant by a dominant gene? What is meant by a recessive gene? How do these differ? What is the genotype of a homozygous dominant organism? What is its phenotype? What is the genotype of a homozygous recessive organism? What is its phenotype? What is the genotype of a heterozygous organism? What is its phenotype? What is a genetic cross? Distinguish between the P, F1, and F2 generations. What is a true-breeding line? What is the genotype and phenotype of a cross between homozygous dominant and homozygous recessive parents? If the F1 progeny are crossed, what would be the genotype and phenotype of the F2 generation? What would be the phenotypic ratio? What would be the genotypic ratio? Be ready to generate Punnet square tests or probability analyses of crosses involving more than one genetic locus. Describe a dihybrid cross where two alleles are homozygous dominant in one parent and homozygous recessive in the other. What would be the phenotypic ratio of the F2 generation from this dihybrid cross? What is meant by independent assortment? Be prepared to calculate probabilities resulting from different crosses.

Distinguish between complete and incomplete dominance. How would incomplete dominance alter the results of a hybrid cross? What would the resulting F2 generation phenotype and genotype ratios be? What is codominance? How does this affect the results of crosses? Be prepared to determine likely blood types of parents based on the blood types of their offspring. What is a polygenic trait? What is a carrier state for a genetic disease? What is meant by linked genes? How does this affect expected outcomes of genetic crosses? How is gene linkage used for chromosomal mapping? Distinguish between autosomes and sex chromosomes. What sex chromosomes are found in women? What sex chromosomes are found in men? What are sex-linked traits? Be prepared to give the results of crosses that involve sex-linked recessive traits. What is the process of nondisjunction? What are the likely results? Why is this important? What is a Barr body? Recognize the genetic abnormality of Downs Syndrome, Turner's Syndrome, and Klinefelter's Syndrome.

1. A species of flowering plant includes plants with blooms that range from bright golden yellow to very pale yellow; no flowers carrying the yellow pigment allele appear white. The allele for yellow flower color:

a. must be a suppressor of another allele.
b. demonstrates incomplete penetrance.
c. demonstrates variable expressivity.
d. must be a modifier of another allele.
e. demonstrates variable penetrance.

2. Coat color in mice is determined by two alleles acting at a single locus: B is dominant and results in mice with black coats, and b is recessive and results in mice with white coats. In a litter of 12 mice, nine are black (B/–) and three are white (b/b). What is the penetrance of the B coat color allele?

a. zero
b. 25 percent
c. 50 percent
d. 75 percent
e. 100 percent

3. Semisterility in nearly 50 percent of the progeny they produce is often an indication that:

a. the parents are translocation heterozygotes.
b. both parents carry pericentric inversions.
c. both parents carry polytene chromosomes.
d. one of the parents carries a chromosomal deletion that removes a telomere.
e. one of the parents carries a chromosomal deletion that removes a chromosome's centromere.

4. A researcher is studying melanoma cells derived from a patient's skin tumor. He determines that all melanoma cells are 2n + 1, but the chromosome number in all normal skin cells is 2n. The 2n + 1 melanoma cells likely arose from:

a. mitotic nondisjunction.
b. meiotic nondisjunction.
c. mitotic recombination.
d. parthenogenesis.
e. colchicine treatment.

5. Why won't a balancer chromosome in Drosophila produce viable crossover products when paired with a wild-type chromosome?

a. Balancer chromosomes contain multiple inversions.
b. Balancer chromosomes contain multiple deletions.
c. Balancer chromosomes have no centromere.
d. Balancer chromosomes have no telomeres.
e. None of the answers is correct.

6. A doctor notes that a patient's genome contains 100 potentially harmful recessive mutations; however, the patient is heterozygous for all of the loci considered and thus does not demonstrate any abnormal phenotypes. The 100 recessive mutations the doctor discovered represent the patient's:

a. bivalents.
b. monosomy.
c.genetic load.
d. amphidiploidy.
e.nondisjunction.

7.The term describing the relationship between the number of copies of a gene and how much product is made from the gene is:

gene-dosage effect.
gene balance.
dosage compensation.
transcription.
aneuploidy.

8. The gene for upright ears in rabbits has two alleles. The E allele is dominant and results in upright ears, and the recessive e allele results in droopy ears. Of 100 rabbits surveyed, 87 had a genotype for upright ears (E/–). However, only 72 of these 87 rabbits had upright ears; the remaining 15 rabbits had completely droopy ears. This suggests that the allele for upright ears:

a. has incomplete penetrance.
b. has complete penetrance.
c. demonstrates variable expressivity.
d. is lethal.
e. is incompletely dominant.

9. A researcher has selfed an autotetraploid plant with the genotype D/D/d/d, and in the resulting progeny she observes a 35:1 phenotypic ratio. What can she conclude from this observation?

a. The progeny from this cross do not demonstrate a standard Mendelian phenotypic ratio.
b. In the 35:1 phenotypic ratio, the 1 represents the phenotype of the d/d/d/d progeny.
c. During meiosis in the D/D/d/d parent plant, it is likely that only bivalents, no quadrivalents or trivalents, formed.
d. It is likely that in this plant species, gametes associate with one another randomly.
e. All of the answers are correct.

10. A researcher is studying fur color in a new species of bats. He notices that fur color, which is due to the presence of a dominant allele (G), ranges from light gray to very dark gray. In addition, some bats that carry a G allele have no fur pigmentation whatsoever; their coats appear white. This is an example of:

a. only variable expressivity.
b. only incomplete penetrance.
c. both variable expressivity and incomplete penetrance.
d. recessive allele lethality.
e. pleiotropy.

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