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Discuss the aetiology, symptoms, prognosis and different diagnostic techniques of acute myeloid leukemia. [25 marks]

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Nelly Stracke
Nelly StrackeLv2
28 Sep 2019
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Related questions

Part 1 Answer the following questions:

A). Typical patients with SCN present very early in life, with recurrent, severe bacterial infections that involved the skin, umbilical stump soft tissues, and lungs, with sepsis. Knowing the mechanism of action of neutrophils, describe why these are the typical characteristics, and why invasive fungal infections are of concern as well.

B) How might one differentiate between increased peripheral destruction of neutrophils and decreased production in the bone marrow as a cause of neutropenia.

C). Michael was diagnosed with acute myeloid leukemia, or cancer of myeloid progenitor cells from the bone marrow. Why was Michael at an increased risk of developing acute myeloid leukemia with a severe congenital neutropenia diagnosis?

What are the differences between acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL)? For each type of leukemia, explain how it originates and the key signs and symptoms.

Highlight any risk factors that might exist, existing medical conditions, present signs and symptoms or complains that the patient is suffering from.

Analyze the results of any diagnostic tests that were performed. Diagnostic tests include, physical exams, blood test, radiologic tests (x-ray, CT scans, etc.), and other functional tests.

Relate the medical treatment used to the underlying pathology.

Propose clinical management plan for the patient’s condition, and possible prognosis.

Case Study #2 K.H. is a 67-year-old African-American man with primary hypertension and diabetes mellitus. He is currently taking an angiotensin-converting enzyme (ACE) inhibitor and following a salt-restricted weight loss diet. He is about 30 pounds over his ideal weight. At his clinic visit his blood pressure is noted to be 135/96. His heart rate is 70 beats/min. He has no complaints. His wife brought a blood pressure cuff and stethoscope with her in the hope of learning to take her husband’s blood pressure at home. A. Risk factors, diagnostic tests, treatment and clinical management plan Highlight any risk factors that might exist, existing medical conditions, present signs and symptoms or complains that the patient is suffering from. Analyze the results of any diagnostic tests that were performed. Diagnostic tests include, physical exams, blood test, radiologic tests (x-ray, CT scans, etc.), and other functional tests. Relate the medical treatment used to the underlying pathology. Propose clinical management plan for the patient’s condition, and possible prognosis. B. Discussion Questions Questions will be made available in Class. Groups will discuss and present answers. Area of focus for questions- Risk factors for hypertension; Treatment of hypertension; Use of ACE inhibitors .

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