Assuming that the mutations are adaptive, how would that affect the stability of a protein at low and high temperatures?
Given:
1) Glutamine to lysine in a warm adapted species.Glutamine is uncharged while lysine is positively charged, therefore there would likely be a change as an uncharged amino acid is being replaced with positively charged amino acid.
2) Threonine to Alanine in a warm adapted species. Threonine is polar uncharged while Alanine is hydrophobictherefore there would likely be a change, as a polar charged amino acid is being replaced with a hydrophobic amino acid.
3) Glutamic acid to aspartic acid in a cold adapted species. Both Aspartic acid to Glutamic acid are negatively charged, therefore, there would likely be no effect with this change as both are negatively charged amino acids.
4) Glycine to alanine in a warm adapted species. Both Glycine to Alanine are non polar amino acids, therefore the change would likely have no effect as both are non polar and hydrophobic.
Assuming that the mutations are adaptive, how would that affect the stability of a protein at low and high temperatures?
Given:
1) Glutamine to lysine in a warm adapted species.Glutamine is uncharged while lysine is positively charged, therefore there would likely be a change as an uncharged amino acid is being replaced with positively charged amino acid.
2) Threonine to Alanine in a warm adapted species. Threonine is polar uncharged while Alanine is hydrophobictherefore there would likely be a change, as a polar charged amino acid is being replaced with a hydrophobic amino acid.
3) Glutamic acid to aspartic acid in a cold adapted species. Both Aspartic acid to Glutamic acid are negatively charged, therefore, there would likely be no effect with this change as both are negatively charged amino acids.
4) Glycine to alanine in a warm adapted species. Both Glycine to Alanine are non polar amino acids, therefore the change would likely have no effect as both are non polar and hydrophobic.
Related textbook solutions
Related questions
Would the subsitution (due to a mutation) of alanine(hydrophobic amino acid) for serine (a polar and hydrophobic aminoacid) have a large or small effect on the structure of aprotein?
| Yes, likely a large effect. The substitution of two chemicallyvery different amino acids could have a large effect on proteinstructure. |
| No, likely little effect. Substituting just one amino acid(even a chemically different one) will not change the overallprotein structure appreciably. |
Which side will generally have a greater amount of matterpresent? The reactants or the products?
| Reactants |
| The products |
| Both will be equal. |
It depends upon the nature of the chemical reaction. |
The Second Law of Thermodynamics suggest that the energy in asystem will...
| tend to become more ordered over time. |
| tend to become more dispersed over time. |
| will tend to transition 'between levels' over time. |
| will mirror the inherent order or disorder of overall system, aproperty known as 'entropy constancy'.. |
