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Choose best answer.Chaperones and chaperonins ...1- Bring the ribosome to the mRNA2- Bring tRNAs to the ribosome3- Assist in correct folding of RNA structure4-Assist in correct folding of protein structure5- Assist in correct folding of chromatin structure

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Keith Leannon
Keith LeannonLv2
28 Sep 2019

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Related questions

In your own words, write a short paragraph for each level of protein structure
(primary, secondary, tertiary, quaternary) and for each describe the types of
interactions. What parts of the protein are interacting with what other parts of the
protein? What types of bonds are used to hold that level of protein structure
together? Are there any patterns of folding that are found in that level of protein
folding? If so, describe them.

Signal sequences are important characteristics of proteins such as halomucin. Which of the options below are true of signal sequences?

Choose all correct answers.

Hints

Choose all correct answers.

found in archaea and bacteria
synthesized near the beginning of translation of a particular protein
may allow the first stages of export to start before synthesis is complete
found at the C terminus of a protein
interfere with folding
found in all proteins intended for export
marks a protein for export by the translocase system
has hydrophobic ends and a polar center

Suggest remedies to problems that may occur in the secretory pathway?

Factors in the secretory pathway that may limit the yield and properties of recombinant products

Factor Effect Remedy?

Codon usage/ No transcript/premature ending of transcription

Protein folding / Incomplete or inaccurate folding leading to product degradation

Glycosylation/ Incorrect glycosylation affecting structure, stability, activity and secretion

Proteolytic processing / Incomplete proteolytic cleavage for activity

Proteolytic degradation / Intra-and extracellular host proteases or attack the foreign gene product

Missorting/ Incorrect or incomplete address tags result in mislocalisation and subsequent degradation of a foreign gene product

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