Question

1) Which one of the following stimulates both insulin andglucagon secretion?

a. hyperglycemia

b. somatostatin

c. cortisol

d. hypoglycemia

e. a high protein meal

2) Which one of the following statements is true?

a. Because it strongly stimulates glycogen synthesis in theliver, cortisol lowers plasma glucose.

b. One would expect insulin secretion to be high duringprolonged fasting.

c. Plasma concentrations of keto acids would be low in a personwith anorexia nervosa.

d. A patient with central (= neurogenic) diabetes insipiduswould likely have decreased ACTH release compared to a healthyperson.

3) A woman suffers from hyperglycemia, abdominal obesity, andskeletal muscle wasting. Lab tests reveal high circulating levelsof ACTH. Which one of the following is the most likely cause of hersymptoms?

a. a hormone-secreting tumor of the adrenal medulla

b. long-term treatment with exogenous glucocorticoids

c. hypercortisolism due to an adrenal tumor that oversecretescortisol

d. hypocortisolism due to autoimmune destruction of the adrenalcortex

e. hypercortisolism due to an ACTH-secreting tumor of theanterior pituitary