answer

watching

views

blushguinea-pig707Lv1

28 Sep 2019

1) In a randomly mating population of fence lizards, haplotype frequencies at the A and B loci are as follows: 60% AB, 10% aB, 10% Ab, 20% ab.

a) Calculate the coefficient of linkage disequilibrium in this population.

b) From your answer, can you infer whether the A and B loci are on the same chromosome?

c) If the population had the same allele frequencies but no linkage disequilibrium, what would be the frequency of the AB haplotype?

answer

watching

208

views

For unlimited access to Homework Help, a Homework+ subscription is required.

You have 0 free answers left.
Get unlimited access to 3.8 million step-by-step answers.

Get unlimited access

Already have an account? Log in

Jarrod RobelLv2

28 Sep 2019

Unlock all answers

Get 1 free homework help answer.

Already have an account? Log in

Related questions

You use a genetic analysis to genotype 250,000 eggs from a rare tropical fish. In the analysis you notice that two loci seem to be in linkage disequilibrium. Therefore, you choose a female that is a double heterozygote for the two loci and genotype an extra 200 eggs from that fish. You observe the following gamete frequencies:

AB = 0.12

Ab = 0.38

aB = 0.35

ab = 0.15

What are the frequencies of the A and the B allele in this population of gametes? What is the coefficient of disequilibrium for these loci?

Please Show Work.

Need help with evolution questions:

1.) A haplotype is best defined as the ________________.

	haploid genotypes of all the gametes produced by a diploid individual

ABO blood type conferred by an individual gamete

genotype of either the paternal or maternal chromosomal complement

multilocus genotype of a chromosome or gamete

2.) Which of the following statements regarding linkage disequilibrium is true?

Exists when D is less than zero, but not when it is greater than zero.

Is reduced by sexual reproduction.

Is increased by crossing-over during meiosis.

Is increased by any random sampling error that happens to create or destroy certain chromosome genotypes but not others.

Is reduced by selection that favors certain combinations of genotypes.

3.) Selection on multilocus genotypes in random-mating populations leads to linkage disequilibrium when _______________.

it reduces mutation rates

it eliminates all haplotypes from the population

it prevents crossing-over during meiosis

some allele combinations confer greater fitness than do others

4.) When two loci are in linkage equilibrium, the allele carried on a chromosome at one locus is independent of the allele carried on the chromosome at another locus. When this is the case, _________________.

allele frequencies will not change over time

the two loci (or, more specifically, their protein products) do not interact

the frequency of each haplotype can be calculated by multiplying the frequency of its two alleles

all possible haplotypes occur at equal frequency

5.) Which of the following accurately characterize(s) Muller's ratchet model for the selective advantage of sexual reproduction?

Drift establishes linkage disequilibrium because multilocus genotypes with few mutations are eliminated by chance events.

In populations without sexual reproduction, deleterious mutations accumulate, eventually imposing such a burden that the population goes extinct.

Sex is favored selectively because it recreates the zero-mutation genotypes lost due to drift.

All of the above correctly characterize Muller's ratchet model for the evolution of sexual reproduction.

6.) The genetic signature of recent positive selection on a locus is _______________.

high frequency and low linkage disequilibrium

low frequency and low linkage disequilibrium

low frequency and high linkage disequilibrium

high frequency and high linkage disequilibrium

7.) Sexual reproduction is advantageous both in changing environments and in constant environments, compared to asexual reproduction.

True

False

8.) Sexual reproduction causes genetic recombination via crossing-over, which combines genotypes from different parents.

True

False

9.) One reason sex may be maintained in natural populations is proposed by the "Red Queen Hypothesis", which states that.....

genotypes created by sex are created by natural selection over and over

recombination creating novel genotypes that can resist infection by parasites

mutation load is reduced by novel adaptive mutations

the ability of sex to fix multiple

1. In a tropical human population in Hardy-Weinberg equilibrium for an autosomal locus determining the presence of pigment in the skin, the frequency of albinism (aa) is 1 in 10,000. What is the approximate frequency of the heterozygotes (Aa)? Please show your work.

2. Variation in horn length in rhinoceros beetles results from allelic variation in a single gene. Assume Hardy-Weinberg equilibrium and determine the allelic frequencies of L1, L2 and L3, genotypic frequencies of long-horned, short-horned and absent-horned beetles in this population. Please show your work.

Genotype Phenotype N

L1/L1

L1/L2 LONG 7500

L1/L3

L2/L2

L2/L3 SHORT 2100

L3/L3 ABSENT 400

3. In a population of African Black Mamba snake, one locus A on chromosome 5 has been found responsible for the aggressive phenotype. It appears that the aggressive phenotype is greatly associated with the body length phenotype locus B, which present in the adjacent locus on chromosome 5. Determine the relationship between these loci using the population data given below. Are these two loci in linkage equilibrium? If not, what is the disequilibrium value for this population? Please show your work

Haplotype N

A1B1 200

A1B2 50

A2B1 100

A2B2 650