Determine whether each of these statements is true or false and then explain why?
a) Myosin II molecules have two motor domains and a rodlike tail that allows them to assemble into thick filaments with motor domains on either end, which is crucial for the efficient sliding of oppositely oriented actin filaments past each other.
b) When activated by Ca2+ binding, troponin C causes a conformation change in the troponin complex that allows tropomyosin molecules to shift their positions slightly so that the myosin heads can bind to the actin filaments.
c) In most animal cells, minus-end directed microtubule motors deliver their cargo to the periphery of the cell, whereas plus-end directed microtubule motors deliver their cargo to the interior of the cell. (Be sure to name these motors).
d) Both kinesin-1 and myosin II move processively making them suitably adapted for their biological functions.
e) Axonemal dyneins mediate the bending of cilia and eukaryotic flagella.
Determine whether each of these statements is true or false and then explain why?
a) Myosin II molecules have two motor domains and a rodlike tail that allows them to assemble into thick filaments with motor domains on either end, which is crucial for the efficient sliding of oppositely oriented actin filaments past each other.
b) When activated by Ca2+ binding, troponin C causes a conformation change in the troponin complex that allows tropomyosin molecules to shift their positions slightly so that the myosin heads can bind to the actin filaments.
c) In most animal cells, minus-end directed microtubule motors deliver their cargo to the periphery of the cell, whereas plus-end directed microtubule motors deliver their cargo to the interior of the cell. (Be sure to name these motors).
d) Both kinesin-1 and myosin II move processively making them suitably adapted for their biological functions.
e) Axonemal dyneins mediate the bending of cilia and eukaryotic flagella.