BIO 361 Lecture Notes - Lecture 17: Hydrolysis, Geometer Moth, John Wiley & Sons
10 Jul 2016
School
Department
Course
Professor
Document Summary
Striated band the result of overlap of two different kinds of primary protein, thick and thin filaments. Cells of striated muscle are fused to form syncytium. Myofibrils themselves are made of individual sarcomere units that account for the banding patterns. Electron microscopy reveals the sarcomere results from mixtures of thick and thin filaments. The key event in muscle contraction relates to the sliding of the thick and thin filaments past each other. Myosin is a dimer of two types of 4 light chains and one type of 2 heavy chains. The light chains clearly associate with the end of the heavy chains that doesn"t have the fibrilar pattern, but rather, a globular portion. The light chains and the globular portion of the heavy chains form the myosin heads. The myosin heads are where enzymatic activity of myosin resides. The working end of the molecule is at the globular blue region (heavy chains).
