Assume the NADH is unable to donate electrons to the electron transport chain due to a mutation in complex I and FAD is the only available electron acceptor in the cell. How many ATPs will be generated by the oxidation of glucose under aerobic conditions if FAD substitutes for all NAD+?

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Sixta KovacekLv2

1 Oct 2018

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The pentose phosphate pathway, an alternative to glycolysis, is used to catabolize five carbon sugars. One ATP molecule and 12 NADPH molecules are produced from one glucose molecule. Glycolysis is the most common pathway for the oxidation of glucose. Two pryuvic acid molecules are the end product. There is a net gain of two ATP molecules and two NADH molecules per molecule of glucose oxidized through glycolysis.

Pyruvic acid loses one carboxyl group, and CO2 is a byproduct, during the transition step. Two carbon acetyl groups are oxidized in the Krebs cycle. Electrons are picked up by NAD+ and FAD for the electron transport system.

5. How does aerobic and anaerobic respiration differ?

6. Hemophilus influenzae requires hemin (X factor) to synthesize cytochromes and NAD+(V factor) from other cells. For what part of cellular respiration are the X and V factors essential?

7. Suppose an individual has mitochondria that leak cytochromes, what effect might this dysfunction have on the ability of the cell to function? Why?

brownkoala747

1.following a meal containing carbohydrates , glucose enters bloodstream and increases circulating blood glucose concentration. describe the changes in the levels of major hormonal regulators in response to hyperglycemia and teh primary functions in reestablishmeing euglycemia (include hormone names and atleast 4 pathways that are being turned on and off to help lower blood glucose concentrations.

2.the glycerol 3 phosphate shuttle system is utilized by skelatal muscle to move elctrons, from NADH generated during glycolosis inbto the mitchondria matrix. this shuttle system uses FAD bound to the mitchondrial glycerol 3 phosphate dehydrgenease enzyme to reduceoxygen to water. the malate-asparate shuttle, found in hepocytes similary uses a series of reduction and oxidation reactions to transfer electrons and reduce NAD+ in mitchondrial matrix to NADH.

based on your knowledge ofelectron transport chain, would you expect a difference in the amount of ATP generated from the reducing equivilents produced via glycolysis in skelatal muscle compared to via glycolosis in the liver? if so what is the foudnation for this difference. if not why are they the same?

Which of the following is common to both aerobic and anaerobicmicrobes?

	Fermentation
	An electron transport chain
	Pyruvate oxidation
	Glycolysis
	All of the above

The primary purpose of catabolism is

	generation of ADP.
	generation of ATP.
	oxidation of NADH to NAD⁺.
	degradation of organic molecules.
	biosynthesis.

What is a fate of pyruvate during alcoholic fermentation byyeast?

	It is reduced to lactic acid.
	It is oxidized to form glucose and carbon dioxide
	It is cleaved to form acetylaldehyde and carbon dioxide.
	It is catabolized in glycolysis.
	It is oxidized to form lactic acid and carbon dioxide.

Electrons needed to reduce an oxidized electron acceptor areprovided by

	a) externally provided compounds such asH<sub>2</sub>, lactate or formate.
	b) an intermediate electron carrier such as NADH.
	c) 0<sub>2</sub>.
	d) Both a and b
	e) All of the above

How are aerobic respiration and anaerobic respirationsimilar?

	Both use oxygen as a terminal electron carrier.
	These are other names for glycolysis.
	Both utilize inorganic molecules as terminal electronacceptors.
	Neither receives electrons from glycolysis.
	Anaerobic respiration does not exist in microbes.

The conversion of phosphoenolpyruvic acid (PEP) topyruvate

	a) releases CO<sub>2</sub>.
	b) involves the conversion of ADP and ATP.
	c) involves substrate-level phosphorylation.
	d) Both a and b
	e) Both b and c

Which of the following is the best definition offermentation?

	The reduction of glucose to pyruvic acid
	The complete catabolism of glucose to CO₂ andH₂O
	The oxidation of a carbohydrate with organic molecules servingas electron donors and acceptors
	The production of ATP from glucose
	The production of ethanol from glucose

A reaction that yields energy has a

	positive ?G_o?.
	negative ?G_o?.
	positive ?E_o?.
	negative ?E_o?.
	negative ?H_o?.

Oxidation and reduction reactions are always coupledbecause

	a) electrons generally accompany protons.
	b) protons generally accompany protons.
	c) electrons cannot exist free in solution.
	d) Both a and b
	e) All of the above

10.

Which of the following is true of aerobic respiration?

	It involves the reduction of oxygen.
	It involves the oxidation of oxygen.
	It involves the reduction of lactic acid.
	It involves the oxidation of lactic acid.
	It does not generate ATP.