How does pathogen clear from the Humoral cell immunity ? please give specifics on the approach of pathogen clearance.
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1. A) What are the main differences between innate and adaptive immunity? B) On which type of immunity do vaccines work?
2. A) What is the difference between humoral and cell-mediated immunity? B) Give an example of each: adaptive cell-mediated immunity, innate cell-mediated immunity, adaptive humoral immunity and innate humoral immunity
For humoral immunity and cellular immunity, give the responding cell, the antigen receptor on the responding cell, and the effector cell(s).
1- The drug chloroquine raises the pH of endosomes, How willthis affect antigen processing and presentation by class IIMHC?
2- A common approach to vaccine development has been the use ofa viral vector such as vaccinia virus to carry genetic informationof a pathogen into an individual. The vaccinia virus infection(which does not cause disease in most individuals) would then leadto production of proteins from the pathogen and an immune response.Such an approach has been very successful for viruses but has notbeen successful for most bacterial infections. Why?
3- The pathogen Listeria monocytogenes enters cellsthrough phagocytosis but escapes from the phagosome before it isdestroyed. Would patients who are deficient in class I MHC bebetter or worse hosts for this pathogen than normal individuals?Why?