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10 Apr 2018

GENETICS : You perform a dihybrid cross between two dogs that are each BbFf. Where not specified otherwise, assume black fur B is completely dominant to white fur b and furry F is completely dominant to hairless f

1. What genotypes at one locus will be epistatic to what genotypes at the other locus, if hair color and hair presence were the only measured phenotypes? (you may find it helpful to write out the genotypes and the phenotypes each would produce, and remember that epistasis is involved in this question).

What phenotypic ratios would you expect in the following scenarios (assume, unless otherwise noted, that the epistasis in part 1 still applies)?

2. Black B is completely dominant to albino b, furry F is completely dominant to hairless f

3. Black displays incomplete dominance to albino , and furry is codominant with hairless

4. Animals that are heterozygous at either locus are black and furry, overriding the other locus' geneotype

5. The black allele B displays epistasis when present at even one copy that masks the effects of the hairless f allele

6. It takes two black B alleles to mask the effects of the hairless f allele

7. Both the black alleles B and furry alleles F are lethal in their homozygous dominant states

8. Both the albino alleles b and hairless alleles f are lethal in their homozygous recessive states

9. Female dogs die when they have homozygous recessive or homozygous dominant states for either locus (dogs use XY inheritance for sex like we do). Note sex of doss in your phenotype ratios.

10. The black allele B although completely dominant, is the only 70% penetrant in heterozygotes and is 90% penetrant in homozygotes for the B allele

11. The hairless allele f is dominant in males and recessive in females

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Deanna Hettinger
Deanna HettingerLv2
11 Apr 2018

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