Salmonella typhimurium is a food-borne bacterial pathogen that can cause severe gastrointestinal disease. Salmonella is often phagocytosed by macrophages that normally destroy bacterial pathogens, but this bacterium is somehow able to prevent the complete maturation of phagolysosomes. Salmonella is able to tolerate the low pH of phagolysosomes, and in fact responds to the drop in pH by secreting toxins that interfere with other cellular responses. You can expect ______________ to contribute to the survival of a bacterium within an Salmonella-containing phagosome, compared to a healthy phagolysosome?
decreased activity of acid hydrolases
increased activity of acid hydrolases
decreased import of H+ ions
increased import of H+ ions
My guess is decreased activity of acid hydrolases but I'm not sure.
Salmonella typhimurium is a food-borne bacterial pathogen that can cause severe gastrointestinal disease. Salmonella is often phagocytosed by macrophages that normally destroy bacterial pathogens, but this bacterium is somehow able to prevent the complete maturation of phagolysosomes. Salmonella is able to tolerate the low pH of phagolysosomes, and in fact responds to the drop in pH by secreting toxins that interfere with other cellular responses. You can expect ______________ to contribute to the survival of a bacterium within an Salmonella-containing phagosome, compared to a healthy phagolysosome?
decreased activity of acid hydrolases
increased activity of acid hydrolases
decreased import of H+ ions
increased import of H+ ions
My guess is decreased activity of acid hydrolases but I'm not sure.