PCB 4674 Chapter Notes - Chapter 7: Allele Frequency, Genotype Frequency, Mendelian Inheritance

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Mendelian genetics in populations ii: migration, drift, and nonrandom mating. Final assumption of hw: the individuals in the population mate at random: here we allow them to mate nonrandomly. Nonrandom mating does not (by itself) caused evolution. Most common type of nonrandom breeding is inbreeding: mating among genetic relatives: increases frequency of homozygotes and decreases frequency of heterozygotes. Conclusion 2 of hw is violated when individuals self- we cannot predict the genotype frequency by multiplying the allele frequencies: deficit of heterozygotes and an excess of homozygotes. Although inbreeding does cause allele frequencies to change, it does not cause genotype frequencies to change: inbreeding by itself is not a mechanism of evolution. Empirical research on inbreeding: because inbreeding creates a large excess of homozygotes, hw analysis can be used to detect inbreeding in nature. California sea otters- more homos than expected, therefore probably inbred. Or what researchers took as one population could actually be two separate populations with different allele frequencies.

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