PCB 4674 Study Guide - Midterm Guide: Inbreeding Depression, Background Selection, Genetic Code

• School: FAU
• Department: Process Cell Biology
• Course: PCB 4674
• Professor: Theisen Timothy C.

Document Summary

Mendelian genetics in populations ii: migration, drift, and nonrandom mating. Homogenize allele frequencies completely: for small populations receiving migrants, migration can act as a potent mechanism of evolution. 7. 2 genetic drift: random evolution- doesn"t lead to adaptation, but does lead to change in allele frequencies. In small populations, hardy-weinberg conclusions can fail due to genetic drift: sampling error: random discrepancy between theoretical expectations and actual results. Random genetic drift: sampling error in the production of zygotes from a gene pool. **sampling error diminishes as sample size increases** The allele frequencies of this new population is likely (totally by chance) different from the parent population- founder effect- a direct result of sampling error. Fst= (ht-hs)/ ht: genetic polymorphism, allele richness, and heterozygosity rise and fall together. Advantageous mutations are exceedingly rare and most alleles are selectively neutral. For most genes in most populations, the rate of evolution is equal to the neutral mutation rate: selectionist theory- john gilespie.