PCB 4674 Chapter Notes - Chapter 6: Effective Population Size, Zygosity, Sewall Wright

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14 Oct 2016

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Mendelian genetics in populations ii: migration, drift, and nonrandom mating. Random fixation of alleles: as any allele changes frequency, it will eventually hit one boundary or the other. Frequency of 0- the allele is lost forever. Loss of heterozygosity: as allele frequencies drift towards fixation or loss, the frequency of heterozygotes declines, heterozygosity: frequency of heterozygotes in a population. Hg+1 is the heterozygosity in the next generation. Hg is the heterozygosity in this generation. N is the number of individuals in a population: fst- fixation index. Ht is expected heterozygosity according to hw. Hs is the average across separate populations. An experiment on random fixation and loss of heterozygosity: fruit flies. More rapidly than expected: because the effective population size was smaller than the actual population size (some may have died before reproducing, or some males may have been rejected as mates, etc. ) Random fixation and loss of heterozygosity in natural populations: ozark lizards.

Related Questions

Q49. Which of the following is NOT true?

If a genetic disease reduces fertility and the allele thatcauses the disease offers no other advantage, the allele willlikely eventually disappear, due to natural selection.

Natural selection does not favor individuals who are homozygousfor the sickle-cell allele, because these individuals typically diebefore they are old enough to reproduce.

Individuals who are heterozygous HbA/HbS areprotected from malaria, and this is why sickle-cell diseasepersists in wetter, mosquito-prone regions in Africa.

In regions where malaria does not occur, individuals who areheterozygous HbA/HbS have a fitness advantageover those who are homozygous for the normal hemoglobin allele(HbA).

Q50. AFTER malaria is cured, the frequency of the HbSallele should decrease in regions with lots of mosquitoesbecause:

People will no longer die from sickle-cell disease in theseregions.

Having one copy of the HbS allele will no longer beadvantageous in these regions.

Natural selection will no longer act on the HbS alleleat all in these regions.

All alleles associated with genetic diseases eventuallydisappear.

Q52. If the frequency ofthe HbS allele is 0.4 in a population, what is thefrequency of the HbAallele (assuming this is atwo-allele system)?

Q53. Which of the following would be sufficient for theHardy-Weinberg equation to accurately predict genotype frequenciesfrom allele frequencies?

p + q = 1

The population is not evolving due to natural selection.

The population is not evolving due to any of the conditions thatdisrupt Hardy-Weinberg equilibrium.

The population is infinitely large.

Q54. In a village, if the proportion of individuals who havesickle-cell disease is 0.25, and the population is assumed to be atHardy-Weinberg equilibrium, what is the expected frequency of theHbS allele? (Hint: What is the genotype of people withsickle-cell disease, and how is that genotype represented in theHardy-Weinberg equation?)

0.1250.250.50.75

Q55. In the same village, what proportion of the populationshould be heterozygous HbA/HbS, according to theHardy-Weinberg equation?

Use the following passage to answer the nextthree questions.

It has been hypothesized that people who are heterozygous forthe allele that causes the deadly genetic condition cystic fibrosis(which, among other symptoms, reduces fertility) are more resistantto the deadly disease tuberculosis.

Q56. If the cystic fibrosis allele protects against tuberculosisthe same way the sickle-cell allele protects against malaria, thenwhich of the following should be true of a comparison betweenregions with and without tuberculosis?

Cystic fibrosis deaths should be more common in regions withtuberculosis.

Cystic fibrosis deaths should be less common in regions withtuberculosis.

Cystic fibrosis deaths should be equally common in both types ofregions.

Regional differences in the cystic fibrosis death rate should bepurely random and unpredictable.

Q57. A person who is heterozygous for the cystic fibrosis allelemoves to a small, isolated community where no one previouslycarried the allele. If the cystic fibrosis allele protects againsttuberculosis the same way the sickle-cell allele protects againstmalaria, what should happen to the frequency of the cystic fibrosisallele in the community over time, and why?

The cystic fibrosis allele should disappear from the population,because a single individual with the allele is not enough for it toproliferate.

The cystic fibrosis allele should increase to a relatively highfrequency, because heterozygotes with the allele will be morelikely to survive than others.

The cystic fibrosis allele should become fixed in thepopulation, due to genetic drift.

The cystic fibrosis allele should either disappear or increasein frequency, depending on chance as well as on tuberculosisprevalence and death rate.

Use the following additional passage to answer the nextquestion.

Suppose you travel to the future, to a time when neithercystic fibrosis nor tuberculosis have caused any deaths for manygenerations. In all of these future populations, thecystic fibrosis allele still exists at a low frequency.

Q58. You visit a huge city with millions of people. If you wereto start sampling the cystic fibrosis allele from one generation tothe next, what should happen to its frequency over the next fewgenerations, and why?

The allele frequency should change a lot from one generation tothe next due to random genetic drift.

The allele frequency should not change much from one generationto the next because the population is large.

The allele frequency should steadily increase due to naturalselection.

The allele frequency should steadily decrease due to naturalselection.

amaranthherring501

Need help with evolution questions:

1.) A haplotype is best defined as the ________________.

	haploid genotypes of all the gametes produced by a diploid individual

ABO blood type conferred by an individual gamete

genotype of either the paternal or maternal chromosomal complement

multilocus genotype of a chromosome or gamete

2.) Which of the following statements regarding linkage disequilibrium is true?

Exists when D is less than zero, but not when it is greater than zero.

Is reduced by sexual reproduction.

Is increased by crossing-over during meiosis.

Is increased by any random sampling error that happens to create or destroy certain chromosome genotypes but not others.

Is reduced by selection that favors certain combinations of genotypes.

3.) Selection on multilocus genotypes in random-mating populations leads to linkage disequilibrium when _______________.

it reduces mutation rates

it eliminates all haplotypes from the population

it prevents crossing-over during meiosis

some allele combinations confer greater fitness than do others

4.) When two loci are in linkage equilibrium, the allele carried on a chromosome at one locus is independent of the allele carried on the chromosome at another locus. When this is the case, _________________.

allele frequencies will not change over time

the two loci (or, more specifically, their protein products) do not interact

the frequency of each haplotype can be calculated by multiplying the frequency of its two alleles

all possible haplotypes occur at equal frequency

5.) Which of the following accurately characterize(s) Muller's ratchet model for the selective advantage of sexual reproduction?

Drift establishes linkage disequilibrium because multilocus genotypes with few mutations are eliminated by chance events.

In populations without sexual reproduction, deleterious mutations accumulate, eventually imposing such a burden that the population goes extinct.

Sex is favored selectively because it recreates the zero-mutation genotypes lost due to drift.

All of the above correctly characterize Muller's ratchet model for the evolution of sexual reproduction.

6.) The genetic signature of recent positive selection on a locus is _______________.

high frequency and low linkage disequilibrium

low frequency and low linkage disequilibrium

low frequency and high linkage disequilibrium

high frequency and high linkage disequilibrium

7.) Sexual reproduction is advantageous both in changing environments and in constant environments, compared to asexual reproduction.

True

False

8.) Sexual reproduction causes genetic recombination via crossing-over, which combines genotypes from different parents.

True

False

9.) One reason sex may be maintained in natural populations is proposed by the "Red Queen Hypothesis", which states that.....

genotypes created by sex are created by natural selection over and over

recombination creating novel genotypes that can resist infection by parasites

mutation load is reduced by novel adaptive mutations

the ability of sex to fix multiple

As temperatures in an African savanna increase and rainfall decreases, it would most likely change into

tiaga

desert

tropical rainforest

temperate forest

What is imprinting? Give an example.

fixed assocation, such as hatching ducks recognizing the first animal they see as their mother

a learned behavior, such as a wasp circling during a search for food, so that it can return to its nest

alteration of instinct, such as a spider changing the type of web it weaves depending upon the environment

Opportunistic species

provide extensive care for their offspring

produce many offspring

reproduce later in life

What are the five agents of microevolution?

gamete production; mating; fertilization; caring for offspring; formation of herds

photosynthesis; respiration; mitosis; meiosis; fertilization

mutation; gene flow; nonrandom mating; genetic drift; natural selection

Microevolution is

new species

minor extinction of species

changes in allele frequency in a population

Which of the following is does not help defend against predators?

Toxins made by plants that injure caterpillars feeding on the plant

The large eyespots on a moth's wing that can startle a hungry bird

Thorns on a plant

Many plants have brightly colored fruit and flowers

Humans have a favored birth weight, neither too small nor too large. This is

stabilizing selection

disruptive selection

artificial selection

directional selection

What is a keystone species?

the first organism that populates an area

an organism upon which the entire ecosystem depends

the first fossils found in the earliest rock strata

As temperatures in the Arctic warm, which of the following changes may occur?

Tundra will be replaced by taiga

Taiga will be replaced by tundra

Temperate forest will be replaced by taiga

Tundra will be replaced by desert

Taiga will be replaced by temperate rain forest

What is desertification?

restoration of vegetation and water to deserts

areas adjacent to deserts also become deserts

abandonment of a habitat by animals

Evolution occurs at the level of

individuals

populations

communities

The maximum population that the environment can support is called the

biotic potential

environmental resistance

carrying capacity

replacement reproduction

demographic transition

A population with relatively more pre-reproductive individuals is common in _____-developed countries

less

Endangered species sometimes breed in captivity. Why are such species endangered in the wild?

Their population density is too high

Loss of habitat

Their environment is polluted

Abiotic components of an ecosystem include

only animal life

only plant life

living components only

nonliving components only

both living and nonliving components

Carbon returns to the atmosphere

as carbon dioxide

from respiration of plants

by the burning of fossil fuels

from respiration of animals

All of the answer choices are correct

Why does the Tropical Rain Forest contain an abundance of antibiotic compounds?

The area is crowded, leading to random production of useful compounds

The area is wet. plants had to develop resistance to fungi and bacterial infections

There is a great diversity of plants, leading to random production of useful compounds

The carrying capacity of the environment for a species is determined by

the reproductive rate of the organism

the number of organisms of that species

the state and national wildlife laws pertaining to that species

a complex

the limited productivity of the environment and the environmental resistance to the biotic potential of the organism

An introduced species that breeds and spreads is

resourceful

harmful

native

dominant

invasive

What is disruptive selection?

environmental influences that select against change

environmental influences that promote one phenotype versus all others

environmental influences that promote two or more phenotypes versus all others

Natural selection acts on

individuals

populations

communities

Two populations of birds live in the same area but have different sleep/wake cycles. This is

behavorial isolation

mechanical isolation

geographical isolation

temporal isolation

An insect that resembles the face of a snake avoids predation by

camouflage

warning coloration

mimicry

chemical defense

mutualism

Unselfish acts that help others in a group so that they increase their chances of surviving and reproducing is called

imprinting

mimicry

altruism

learning

instinct

If an environment changes rapidly, organisms with ____ will be more likely to survive and reproduce.

the correct allele frequency

existing neutral mutations

existing beneficial mutations

How did geology influence Darwinâs thoughts?

It demonstrated that the earth was very old, therefore there was enough time for species to evolve

it demonstrated that all continents were similar

it demonstrated the presence of many fossils

The founder effect occurs when

large groups of individuals leave their home population and establish new settlements, mating only among themselves

many members of a population die, resulting in a great loss of genetic diversity

many members of a population reproduce causing too much genetic diversity within the population

small groups of individuals leave their home population and establish new settlements, mating only among themselves.

The greenhouse effect is due to high atmospheric

Nitrogen

Ammonia

Carbon monoxide

Carbon dioxide

Oxygen

What are the Reproductive Barriers that keep species separate?

lack of food; lack of habitat; lack of potential mates; lack of nesting sites; lack of genetic variation

mountains; canyons; glaciers; bodies of water (for terrestrial animals); areas of land (for aquatic animals)

habitat isolation; temporal isolation; behavioral isolation; mechanical isolation; gamete isolation

What is directional selection?

environmental influences that select against change

environmental influences that promote one phenotype versus all others

environmental influences that promote two or more phenotypes versus all others

Which of the following is correct when describing a predator-prey cycle?

A decline in the numbers of predators causes a decline in the number of prey

A decline in the numbers of prey causes a decline in the number of predators

An increase in the number of predators triggers an increase in the number of prey

An up-and-down cycle will be seen for the prey animal

A seasonal die-off that will occur without the other species present

Why are top-level predators (lions, eagles, humans) so rare in a community?

Only a small amount of the energy is passed from one trophic level to the next

They do not breed as fast as other animals

Because of predation by higher predators

It is difficult for them to learn how to capture prey

Their job is to keep the population size of other animals in check

Alleles conferring bright color to male guppies are common because

they make males less visible to predators

they help males identify each other

they are preferred by females

Organisms that obtain their energy from producers or other consumers are

autotroph

heterotroph

producer

autotroph and producer

heterotroph and producer

What is the environmental impact of strip mining?

lack of trees exposes the surface of the earth, promoting runoff and loss of adjacent trees

removal of minerals from the soil hampers growth of vegetation

it causes a potential increase in volcanic activity

Two populations of squirrels are separated by a mountain range and would not be capable of interbreeding. This is an example of:

behavorial isolation

mechanical isolation

geographical isolation

temporal isolation

What is a danger of overfishing?

humans will become dependent upon fish

selection for smarter fish that can avoid being caught

driving the population back into the lag phase

What is meant by prezygotic versus postzygotic speciation mechanisms?

before versus after formation of a zygote

before versus after meiosis

before versus after gamete formation

The relatively short term changes in allele frequencies within a species or population is

artificial selection

microevolution.

speciation

macroevolution

Avoidance of a location with predators is the result of

imprinting

mimicry

altruism

learning

instinct

What is the difference between Density-Dependent and Density-Independent Factors on populations?

density-dependent factors exert a greater influence when there are more individuals; density-independent exerts the same influence on all individuals regardless of their number

density-dependent factors exert a greater influence on larger, more dense individuals; density-independent factors exert the same impact on individuals of all size

density-dependent factors exert the same influence on all individuals regardless of their number; density-independent factors exert a greater influence when there are more individuals regardless of their number

All of the organisms in a given location or area is termed a

peer group

flock

community

population

herd

The concentration of the pesticide DDT would be highest in

a minnow

a mosquito larva

a seagull

plankton

algae

Our biosphere is

the Earth

the atmosphere

the ocean

land on Earth

fresh and salt water

What is meant by âcarrying capacityâ?

the amount of food produced in an ecosystem

the extent of energy required to maintain an ecosystem

the number of individuals that can be supported by an ecosystem

Species living on another is

resource partitioning

coevolution

symbiosis

predation

niche sharing

One species feeding on another is

competition

a community

an ecosystem

predation

symbiosis

Populations of different species interacting with one another in a natural environment is called

competition

a community

a biome

predation

symbiosis

Which of the following is not a biogeochemical cycle?

ATP cycle

water cycle

carbon cycle

phosphorus cycle

nitrogen cycle

Horses became larger and faster to escape predators. This is

stabilizing selection

disruptive selection

artificial selection

directional selection

PCB 4674 Chapter Notes - Chapter 6: Effective Population Size, Zygosity, Sewall Wright

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