BIOL 3051 Chapter Notes - Chapter 12.1: Pantoprazole, Esophagogastroduodenoscopy, Omeprazole

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Treatment guidelines for non-h. pylori and non-nsaid ulcer: Antisecretory therapy with a ppi (e. g. omeprazole 20 - 40 mg daily) Duration of initial therapy - 4 weeks. Duration of initial therapy for gastric ulcer - 8 weeks. Perform a repeat upper endoscopy with biopsies to determine the etiology after completion of initial ppt therapy. Maintenance therapy: continue long-term ppi therapy for h. pylori negative, nsaid negative ulcers. Focus of treatment = acid suppression with ppi (safe in pregnancy) H. pylori positive antimicrobial treatment deferred until after delivery. No significant adverse outcomes with ppi use in pregnant women (study based on omeprazole and pantoprazole) Omeprazole and pantoprazole are excreted in breast milk, but at very low levels. Non-pharms not significant in pud; significant in gerd. Don"t have a large role in pud (compared to gerd, where non-pharmacological. Blood transfusions are only given when hbg (hemoglobin) levels are really low (

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