Biology 1002B Chapter Notes - Chapter Outcomes: Experimental Evolution, Bacteriostatic Agent, Citric Acid
2 May 2019
School
Department
Course
Professor
Document Summary
Characteristics of model systems that can be used for experimental evolution. Any organism that divides rapidly and gives rise to offspring fast. Measuring relative fitness in e. coli w= growth rate of evolved strain/growth rate ancestral strain. Assess what it means for w to be or = to 1 w=1 -> no adaptation w>1 -> adaptation w<1 -> maladaptation. Design of lenski"s long term evolutionary experiment (lee) with e. coli. Use a large population size since beneficial mutations are rare. 12 identical populations were started in liquid media. Prolong the life and the number of cells in a culture. Where citrate enters metabolism (not explicitly mentioned in video). Role of glucose limitation in the experiment and the role of citrate. Can increase growth rate if glucose runs out. What is the cit+ phenotypethat is what did the researchers detect that was different in the. Increase # of cells compared to the other liens.
