Biology 1002B Lecture Notes - Lecture 12: Tetrachromacy, Chromosome, Cone Cell
19 Dec 2017
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Characteristics of model systems that can be used for experimental evolution: all have short generation time (viruses, bacteria, chlamy, drosophila, yeast) can be 20 mins to a week, asexual (no recombination) Where citrate enters metabolism: citrate keeps iron in soluble form in solution so it can be taken up, only enters the cells under aerobic conditions. How to determine if cit+ phenotype arose from one single mutation or was dependent on previous mutations: cit+=ability to use citrate as carbon source. Result of replaying evolution of cit+ phenotype: was the cit+ phenotype the result of a unusually rare mutation or contingent upon prior mutations. If it was a rare mutation the rare mutation concentration would be pretty constant. If it was contingent, based on another mutation, (potentiation) would not be constant: take frozen ancestral samples allow them for grow for another 3,700 generations, do they evolve cit+ phenotype nothing before 20,000 got you.
