Biology 1002B Lecture Notes - Lecture 25: Opsin, Continental Drift, Trichromacy

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Lecture 24 characteristics of model systems that can be used for experimental evolution. Transform one set with a gene that produces a red colour. Subject the red flask to some change in the environment for 2000 generations. Leave the ancestral strain alone, freeze them so that they are suspended. Mix them together, subjected to the same changed environment. Can see the proportion of red cells vs. white cells. Measure w, relative fitness of the ancestral and evolved strains. W<1 maladaptation design of lenski"s long term evolutionary experiment (lee) with e. coli. 12 flasks, each needs to be transferred to fresh growth medium for 24 hours (when all the glucose is consumed) Every 500 generations (75 days) freeze 500 million cells. 6. 6 generations per day, 50000 generations after 2010. All just sitting and growing, no change in the solutions. Equivalent to doing it for humans for 1. 2 million years value of cryopreservation to lee.

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