NURS 2004 Chapter Notes - Chapter 12: Alanine, Barbiturate, Suxamethonium Chloride

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Adverse drug reactions = any noxious, unintended and undesired effect that occurs at normal drug doses (range from mildly annoying to life threatening). Adverse events are most common in the elderly and the very young (patients over 60, account for nearly 50% of all adr cases). More common in people taking more than one drug. Side effect = a nearly unavoidable secondary drug effect produced at therapeutic doses. Some side effects as soon as the drug is taken while others take weeks or months to develop. Toxicity = an adverse drug reaction caused by excessive dosing. Severe adr- can occur with normal dosing of drugs (some cancer drugs, cause decrease in. Rbc"s, this decrease opens patients up to infection even though it is being administered therapeutically). Once the immune system has been sensitized to a drug, re-exposure to that drug can trigger an allergic reaction.

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