MCD BIO CM156 Study Guide - Midterm Guide: Threshold Model, Human Genetics, Twin
23 Feb 2020
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Assumptions: mono and di- twins share the same environment of the mother in utero. Mono-share 100% of gene di- 50% of genes. The more genes, the more classes that lead to the effect of height. You can use medelian trait inheritance to explain complex trait inheritance. Many genes are acting to create a distribution. By environment? inherited certain regions of genome from ancestor. Can follow genome material all the way to you. Calculating variability is by calculating regions from relativese. Formula where you have an expected number and an observed number and calculate a p-value for it. Not looking at the expression of the snp (dna variation, insert or deletion variation). It is merely a genetic variance that might have consequence. If a snp is associated with a trait, the reason for that is because the snp is causal or there is linkage disequilibrium that creates a causal situation (or error) Asking if any snps go along with the trait.
