Biology 3593B Study Guide - Quiz Guide: Programmed Cell Death, Nuclear Membrane, Apoptosis
Document Summary
Learning goals: difference between apoptosis and necrosis, mechanism and influence on organism. Size and growth is determined by cell division and death. At times there is massive cell death. Cell death can be used either to create or break down structures depending on need: Our own hands and feet are sculpted by apoptosis during embryonic development: they start out as spadelike structures, and the individual fingers and toes separate because the cells between them die. Tadpoles lose their tail when changing into a frog. Programmed cell death: the cells activate an intracellular death program and kill themselves in a controlled way. Cells shrink, condense, cytoskeleton collapses, nuclear envelope disassembles, nuclear chromatin condenses and breaks up into fragments. Cell breaks up into membrane-enclosed fragments: apoptotic bodies. Cell necrosis: animal cells that die accidentally in response to acute insult (trauma/lack of blood) Cells swell and burst spilling their contents over their neighbors inflammation. Structure they form is no longer needed.
