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What is the antonyms of zigzag?

How menstruation linked with ovulation?

What if we divide 2 and 0?

Nootkatone one of the chemicals responsible for the odour and taste of grape fruit, shows a molecular ion a M/E= 218 in its mass spectrum and contains carbons, hydrogen, and oxygen.

Suggest several possible molecular formular for nootkatone. How many degrees of unsaturated (double bonds & rings) are indicated.

Is the mutation harmful beneficial or neautral

After reading answer briefly answer the 3 questions. 

One of the oldest medications still used often in clinical practice is heparin. It was founded in 1916 before the Food and Drug Administration was created. Generated nearly solely from pigs' mucosal tissues. (Hedlund, 2013) The market for heparin depends on China because of its sizable swine herds. The drug's supply chain starts at slaughterhouses, then moves on to tiny workshops that collect heparin crude by removing the mucous membranes from pig intestines. Then, after being further refined into an active pharmaceutical component, the crude heparin is sold to other facilities, often via consolidators (API). In order to generate a completed heparin product, such as an injectable pharmaceutical vial, this API is then mixed with inactive components (typically a sterile solution). (Heparin: A Wake-Up Call on Risks to the U.S. Drug Supply, 2012)

The drug heparin was recalled on a global scale in 2008. Numerous fatalities and adverse events were found to be caused by a contaminate identified as oversulfated chondroitin sulphate, according to researchers. (Hedlund, 2013) 81 individuals died as a result of it.  Eventually, it was discovered what triggered the undesirable effect that resulted in the fatalities and injuries. The contaminated chemical was an over-sulfated derivative of chondroitin sulfate, a similarly comparable compound derived from animal or fish cartilage and frequently used as an arthritis therapy. Since over-sulphated chondroitin is not a naturally occurring molecule, it is not as expensive as actual heparin starting material, and it matches the in-vitro characteristics of heparin, the fake was very definitely made intentionally rather than by mistake during production. The contamination was caused by a combination of a lack of appropriate pigs in China and cost-effectiveness, also it was discovered that the raw heparin batches had been reduced by 2 to 60% with the fake chemical. (Chinese Heparin Manufacturer Again Involved in Falsification and GMP Non-Compliance - ECA Academy, 2016)

Following the adulteration, investigations revealed that OSCS was present in both the finished heparin API produced by SPL-CZ and the raw material sent to the firm by Chinese contractors. The specific source or suppliers of the heparin adulteration are still unknown to Baxter and the FDA; however, evidence shows that OSCS was most certainly introduced by organizations upstream of the Chinese API production facility, Scientific Protein Laboratories-Changzhou (SPL-CZ). Starting in 1996, Chinese raw materials have been used to make Baxter's heparin API; SPL-CZ joined the company's heparin production process in 2004. (Heparin: A Wake-Up Call on Risks to the U.S. Drug Supply, 2012)

The U.S. Centers for Disease Control and Prevention (CDC) started looking into an epidemic of unanticipated allergic-type responses in dialysis patients in early 2008, which started in 2007. The majority of them had received heparin intravenously from Baxter Healthcare. Additional analysis found that oversulfated chondroitin sulphate (OSCS), an artificial adulterant with hazardous effects, had been added during the production of heparin in China. Given its close resemblance to the original medication, routine testing was unable to identify OSCS, which is produced for roughly a hundred times less than heparin. (Heparin: A Wake-Up Call on Risks to the U.S. Drug Supply, 2012)A number of Americans experienced negative effects, including fatalities. At least 11 medication items and 72 healthcare products containing heparin were recalled by 14 additional American companies, including Baxter Healthcare, the main heparin producer in the United States. Heparin items were already suspended in Australia, Switzerland, Sweden, Denmark, Germany, France, and Italy as per regional health organisations and press sources. (Heparin: A Wake-Up Call on Risks to the U.S. Drug Supply, 2012)

The heparin scandal exposed a variety of supervision and supply chain management mistakes. Despite not doing a pre-approval examination, the FDA accepted SPL-CZ as a source for Baxter, in part because it mistook SPL-CZ for another website in its database. Investigators from Baxter were not allowed entry to upstream factories and aggregators in 2008 when they attempted to retroactively review their supply chain. (Heparin: A Wake-Up Call on Risks to the U.S. Drug Supply, 2012) Two heparin upstream consolidators were likewise off-limits to the FDA. Baxter started receiving heparin API produced by SPL-CZ in 2004, but somehow it didn't verify the facility until 2007; instead, it relied on an earlier evaluation by a separate business. A variety of production quality concerns were discovered during the investigation of SPL-CZ after the FDA discovered that it had been adulterated, including inadequate quality control procedures for incoming raw materials. SPL-CZ was not licensed by the Chinese State Food and Drug Administration since it was considered a chemical facility in China. It therefore probably received no supervision from the Chinese government. (Heparin: A Wake-Up Call on Risks to the U.S. Drug Supply, 2012)

Questions:

1. To avoid another situation like heparin adulteration in the future what steps should be taken by the government to protect people?
2. What could have been the major reason behind heparin adulteration? 
3. Do you think heparin contamination was intentional? Why or why not?

sources: 

1. Chinese Heparin Manufacturer again involved in Falsification and GMP Non-Compliance. (2016, march 2). Retrieved from gmp compilance:  [Accessed on: 2023 February 5]

Calculate the number of moles of solute present in 500 mL of a 0.75 M solution of magnesium chloride (MgCl2).

You make a Language service API call.

You call the following URL.

You send the following request body.

{

  "documents": [

    {

      "language": "en",

      "id": "1",

      "text": "Our tour guide took us up the Space Needle during our trip to Seattle last week."

    }

  ]

}

You receive the following response body.

{

  "statistics": {

    "documentsCount": 1,

    "validDocumentsCount": 1,

    "erroneousDocumentsCount": 0,

    "transactionsCount": 1

  },

  "documents": [{

    "id": "1",

    "score": 0.5,

    "statistics": {

      "charactersCount": 80,

      "transactionsCount": 1

    }

  }],

  "errors": []

}

The showStats=true parameter results in a statistics node in the API response.

Select Yes if the statement is true. Otherwise, select No.

Select only one answer.

1.  Yes

2.  No

Give a social/personal example of a social movement that you are passionate about.  Who are they?  What do they value?  What do they do to get their message across to society?  In your answer you must USE, DEFINE and BOLD the following concepts: social movement and ONE of the following concepts: civil disobedience, relative depravation OR resource mobilization.

A two-word fragment of the first document has multiple possible entities associated with it.

Select Yes if the statement is true. Otherwise, select No.

1. yes

2. No

ou are designing a chatbot for a restaurant.

You plan to enable users to make reservations. The solution must ask the users to provide multiple specific types of information necessary for the reservation.

What type of dialog should you use?

Select only one answer.

Compare the philosophies of liberalism republicanism and a scripticism, and give examples of

how they are reflected in the constitution of 1787

Provide examples of how both the strengths and weaknesses of the Articles of Confederation were reflected in the Constitution of 1787.

What is the ph of 0.0333M. hno3?

What are [h3o=][oh-] and poh with of 9.85?

Signed a deal with Under Armour, where UA will pay Curry $4M every year, starting from 1/1/2023, for 5 years. In return, UA expects to make $2M, $5M, $10M, $20M and $30M profit from Curry's brand for the 5 years. Suppose the profits are earned on the first day of each year from 2024 to 2028. The discount rate is 10% per year. What was the NPV of this contract for Stephen Curry at the time of 1/1/2023?

If we do things right, there is nothing to fix. Discuss this statement in relation to the cost of quality where prevention, appraisal, internal failure and external failure constitute cost of quality. How does this align with the philosophical stance of Philip Crosby?

What are the 'areas of jurisdiction' in the brain called?

C. fissures

B. lobes

A. cortex

List three ways in which bound labor is different before 1660 than what developed after 1660 and became what we known as slavery in the US.

Indigenous religions normally emerge out of peoples relationships with nature. Why do ancient and indigenous people tend to see nature and natural forces as divine?

In a formal expository paragraph of approximately 230 words, support this statement:

The lives of teenagers today are more difficult then the lives of teenagers 60 years ago.

What was the historical use , look, and feel of the phone?

Describe what the cell phone is ,it’s origin, and its purpose?