ayishashaji9961

Help in these questions if possible! Thank you sm 

Briefly explain the roles that nonhistone proteins play when associated with chromosomes. Why do chromosomes have more different types of nonhistone proteins than histone proteins?

The human genome contains about 3 billion base pairs. During the first cell division after fertilization of a human embryo, S phase is approximately 3 hrs long. Assuming an average DNA polymerase rate of 40 nucleotides/second, what is the minimum number of origins of replication you would expect to find in the human genome?

List 3 examples of types of mutations that would disrupt the process of mitotic chromosome segregation. How could you use yeast artificial chromosomes (YACs) to find these types of mutations in S. cerevisiae?

What DNA sequences are found at the telomeres of human chromosomes? Briefly explain the function of the two telomere-associated complexes (telomerase and shelterin).

1. How many kinds of 5-membered rings are in DNA?

Which of the following statements concerning the vertebralcolumn is true?

a. The adult vertebral column is composed of 24 bones.

b. All vertebrae have an anterior body.

c. The sacrum results from the fusion of five vertebrae.

d. The vertebral column has five major curvatures.

e. The thoracic vertebrae are located inferior to the lumbarvertebrae.

i need to know the total number of vertebrae in posterior curvatures + number of bones in one orbit

Number bones in human body?

SCENARIO: During medical examinations of the poor, a nurse observes that several of the patients smoked and had high blood pressure. The nurse reviewed the related literature and found that smoking and high blood pressure shared a positive relationship. The nurse believed that poverty may have an additive influence to smoking relationship with high blood pressure. The nurse decided to conduct an investigation into this relationship. The nurse collected data on over 100 patients. The data collected were blood pressure (high or low), smoking (currently smoking, not currently smoking but smoked in the last year, never smoked), and poverty. Poverty was measured as a self report by the patient. The nurse used a partial bivariate correlation to analyze the data. The nurse found that while controlling poverty, that smoking still had a positive relationship with high blood pressure.

Questions:

1. What kind of study is this according to the methodology used? Justify your choice. (10 points)

1. Write a research hypothesis/hypotheses or question(s) for this study and identify the independent and dependent variables in the study. (10 points)

1. Critique the internal and external validity of the study as it is designed. (20 points)

1. Critique the data analysis used in the study. (20 points)

1. If you were going to conduct this study, how would you redesign to enhance its validity and at the same time make it reasonable to conduct? In your redesign be sure to address the appropriateness of using self-report poverty and the statistical procedure(s) that you would use to analyze data. (40 points)