PLEASE TYPE YOUR ANSWER WHICH COVERS ALL PARTS
A) Compare and contrast base substitution, insertion, and deletions mutations AND Compare and contrast silent, missense, and nonsense mutations.
B)What is a frameshift mutation, and what type of DNA mutations cause frameshift mutations?
C) What type of DNA mutation is most likely to cause a silent mutation AND Why are insertion and deletion mutations often much more harmful to organisms than base substitution mutations?
D) What is the difference between horizontal gene transfer and vertical inheritance?
PLEASE TYPE YOUR ANSWER WHICH COVERS ALL PARTS
A) Compare and contrast base substitution, insertion, and deletions mutations AND Compare and contrast silent, missense, and nonsense mutations.
B)What is a frameshift mutation, and what type of DNA mutations cause frameshift mutations?
C) What type of DNA mutation is most likely to cause a silent mutation AND Why are insertion and deletion mutations often much more harmful to organisms than base substitution mutations?
D) What is the difference between horizontal gene transfer and vertical inheritance?
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Part B
Think about the DNA coding sequence of a gene. If an A were swapped for a T, what kind of mutation could it cause and why?
| a) It could cause a frameshift nonsense or frameshift missense mutation because it would change the reading frame of the codon triplet. | ||||||||||||||||||||||||||||
| b) It could cause a silent, missense, or nonsense mutation because those are the types that can be caused by a nucleotide-pair substitution like this one. | ||||||||||||||||||||||||||||
| c) It could cause a nonsense mutation because the sequence would no longer be the same, so the protein would be shorter and non-functional. | ||||||||||||||||||||||||||||
| d) It could cause a silent mutation because A and T are complementary to each other so it is not really a substitution mutation. Part C Why is a frameshift missense mutation more likely to have a severe effect on phenotype than a nucleotide-pair substitution missense mutation in the same protein?
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