Regarding Musculoskeletal Alterations Explain how the management of the gout disease/disorder relates to the pathophysiology. Are any new treatment options on the horizon? Please explain.

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vincent040899Lv1

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What type of inhibition would you expect to be displayed by allopurinol? For gout treatment? My answer is below. Is it correct? Please explain. When allopurinol is given, it would block xanthine oxidase, this route would no longer be open. The gout patient would presumably start excreting xanthine and hypothanthine instead of urate. Their serum levels of these products would also elevate, perhaps leading to toxic effects. The fact that xanthine and hypoxanthine are more soluble than urate might lead to increased fluid loss.

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Hello can someone help me with my case study and critical thinking questions please... appreciate it.

A couple that met at a Cystic Fibrosis Society support group is contemplating having children. They both had brothers who developed cystic fibrosis and they are concerned about the likelihood of having sons who have the disease. As a counselor, you are to answer the following two genetic counseling consult questions in addition to the five critical thinking questions that are listed below.

Genetic Counseling Consult Questions (To Answer)

What is the likelihood that any of their children (sons and/or daughters) will be born with the disorder?

What is the likelihood that any of their children (sons and/or daughters) will be carriers of the disorder?

Critical Thinking Questions (To Answer)

What are the main presenting issues? Include why they may have arisen. (Noteâin this case, you are to assume that they have a child who presents with cystic fibrosis.)

Identify and use at least one website that you used to learn more about the issues and potential solutions; briefly explain what was found at the website(s).

What is (are) the potential disease or disorder? Include (a) a justification for your decision, (b) the causal agent, and (c) the mode of transmission.

What is the recommended treatment for the most likely disease or disorder you identified?

What is the prognosis for the disease or disorder (a) without treatment and (b) with treatment?