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19 Nov 2019
11. The field of tissue engineering is highly multidisciplinary and draws on experts from clinical medicine, mechanical engineering, materials science, genetics, and related disciplines from both engineering and the life sciences. The field relies extensively on the use of porous 3D scaffolds to provide the appropriate environment for the regeneration of tissues and organs. These scaffolds essentially act as a template for tissue formation and are typically seeded with cells and occasionally growth factors, or subjected to biophysical stimuli in the form of a bioreactor a device or system which applies different types of mechanical or chemical stimuli to cells. Typically, two types of biomaterials, synthetic polymers and natural polymers, are used in the fabrication of scaffolds for tissue engineering. Each of these individual biomaterial groups has specific advantages and, needless to say, disadvantages so the use of composite scaffolds comprised of different phases is becoming increasingly common. Please describe at least one major limitation that either natural polymer or synthetic polymer has, which needs to be improved and considered in designing biomaterial scaffolds. (4 p) Natural polymer- Synthetic polymer
11. The field of tissue engineering is highly multidisciplinary and draws on experts from clinical medicine, mechanical engineering, materials science, genetics, and related disciplines from both engineering and the life sciences. The field relies extensively on the use of porous 3D scaffolds to provide the appropriate environment for the regeneration of tissues and organs. These scaffolds essentially act as a template for tissue formation and are typically seeded with cells and occasionally growth factors, or subjected to biophysical stimuli in the form of a bioreactor a device or system which applies different types of mechanical or chemical stimuli to cells. Typically, two types of biomaterials, synthetic polymers and natural polymers, are used in the fabrication of scaffolds for tissue engineering. Each of these individual biomaterial groups has specific advantages and, needless to say, disadvantages so the use of composite scaffolds comprised of different phases is becoming increasingly common. Please describe at least one major limitation that either natural polymer or synthetic polymer has, which needs to be improved and considered in designing biomaterial scaffolds. (4 p) Natural polymer- Synthetic polymer
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Tod ThielLv2
19 Nov 2019
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