1. You mate flies that you know are heterozygous for a loss-of-function bicoid mutation and a balancer chromosome. The balancer chromosome, in this case, has a marker that allows one to detect the presence of the balancer in embryos. However, embryos without balancers seem normal. Does this imply Bicoid has no effect? Why or why not?
2. you are working with Arabidopsisdopsis, a model for plant development and two different recessive null loss-of-function mutations have been isolated. The mutations are in different genes but both affect the leaf development (specifically the density of the stomata- openings for gas exchange). The homozygous loss of function phenotype for gene A shows twice as many stomata when compared to wild-type leaves, while the homozygous loss of function for gene B shows four times as many stomata compared to wild-type leaves. A double mutant for both gene A and gene B show four times as many stomata. What is the order of action of these two genes and what is their genetic relationship (i.e. activation or inhibition)?
1. You mate flies that you know are heterozygous for a loss-of-function bicoid mutation and a balancer chromosome. The balancer chromosome, in this case, has a marker that allows one to detect the presence of the balancer in embryos. However, embryos without balancers seem normal. Does this imply Bicoid has no effect? Why or why not?
2. you are working with Arabidopsisdopsis, a model for plant development and two different recessive null loss-of-function mutations have been isolated. The mutations are in different genes but both affect the leaf development (specifically the density of the stomata- openings for gas exchange). The homozygous loss of function phenotype for gene A shows twice as many stomata when compared to wild-type leaves, while the homozygous loss of function for gene B shows four times as many stomata compared to wild-type leaves. A double mutant for both gene A and gene B show four times as many stomata. What is the order of action of these two genes and what is their genetic relationship (i.e. activation or inhibition)?