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19 Apr 2019
After roughly 15 years we have the first malaria vaccine going into phase 4 trials. Meanwhile a Zika vaccine is starting phase 2b trials, only 2-3 years after the first major outbreak in Brazil.
A) Discuss in some detail why it is so much more difficult to develop a vaccine for malaria than for e.g. the Zika or rubella virus. I am looking for at least 2 reasons, and a brief explanation of those reasons. Just stating that one is complex and the other simple is insufficient. If that is what you want to say, back it up with facts.
B) Both the CRISPR bacterial defense system and the adaptive immune system in mammals have means to recognize âsignaturesâ of invading organisms. In what way are the two systems different?
After roughly 15 years we have the first malaria vaccine going into phase 4 trials. Meanwhile a Zika vaccine is starting phase 2b trials, only 2-3 years after the first major outbreak in Brazil.
A) Discuss in some detail why it is so much more difficult to develop a vaccine for malaria than for e.g. the Zika or rubella virus. I am looking for at least 2 reasons, and a brief explanation of those reasons. Just stating that one is complex and the other simple is insufficient. If that is what you want to say, back it up with facts.
B) Both the CRISPR bacterial defense system and the adaptive immune system in mammals have means to recognize âsignaturesâ of invading organisms. In what way are the two systems different?
Patrina SchowalterLv2
20 Apr 2019
