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22 Aug 2018

16. Assume that you don't have any information about an individual's parents or offspring. In which of the following, you CANNOT determine the genotype of the individual from his/her phenotype directly and with certainty?

A.

An unaffected individual in an XLD pedigree with complete penetrance

B.

An individual who displays the recessive phenotype of a Mendelian trait

C.

An individual with curly hair (Incomplete dominance)

D.

An affected male with red-green color blindness (XLR)

E.

An affected male with a Y-linked trait

F.

An unaffected teenage child of an affected individual with Huntington (AD), in a population with complete penetrance of this disorder

G.

An unaffected individual who has an affected parent and an affected child in a pedigree with incomplete penetrance

17. John and his maternal uncle both are affected with a cytoplasmic (mitochondrial) trait. John’s mother has passed away. Which of the following is (are) WRONG? Find the best answer.

A.

John’s mother was affected, and transmitted the trait to John.

B.

John’s maternal grandmother was affected

C.

John’s maternal aunt should be affected

D.

All of John’s sibs should be affected

E.

There is no chance for any of John's nephews to be affected.

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Keith Leannon
Keith LeannonLv2
24 Aug 2018
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