Describe the roles of initiator and executioner caspases in apoptosis. Which do inhibitors of apoptosis (IAPs) interfere with?
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Briefly explain the main characteristics of the programmed cell death (apoptosis) of a cell and how they can be used to study apoptosis.
Explain why the detection of caspases 3,7 can be used to study apoptosis.
What is the principle behind the fluorescent staining of apoptotic cells with CellEvent⢠Caspase-3/7 Green Detection Reagent?
Immunology:
1. What is the role of IL-2 and IL-2 receptor in activation of naive T cells?
2. How do CD8+ T cells become activated by dendritic cells?
3. How are apoptotic cells recognized by macrophages? It is through caspases?
4. Describe how a CTL causes apoptosis in its target cell.
How do Cells Attach to the ECM?
Integrins: Apoptosis: What are triggers? What does this cause in cell? What is importance of location of PS (phosphatidyl serine) in cell membrane? Caspases (role and examples of targets in cell) Apoptosome (look at role of cytochrome c)