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19 Feb 2018

Briefly define the following terminology:

(a) Cocaethylene

(b) cocaine bugs

(c) methoxsalen (note: your answer should be related to quitting smoking)

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Reid Wolff
Reid WolffLv2
20 Feb 2018

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Related questions

Researchers are always looking for new ways to deliver therapeutic drugs to the bloodstream for distribution throughout the body. Currently, biomedical research teams are using epithelial tissue cultures to investigate a relatively new approach to drug introduction. For some time, science has known that certain compounds are easily absorbed by epithelial membranes and picked up by the blood. For example, patches of material containing drugs that inhibit motion sickness have been used by tourists on cruises. Smokers, trying to stop the nicotine withdrawal commonly associated with quitting smoking, have used nicotine patches. Patients with heart disease or burns often receive therapy by means of similar patches. Today, however, researchers are looking for wider and more varied uses of epithelial absorption as a drug delivery method.

1. a) Based on what you know of the different epithelial tissue types, which are the best candidates for this type of therapy? Explain your choices.

b) How could a clinician actually apply epithelial absorption techniques? Try to think of strategies other that the skin-patch approach.

c) Explain some of the harmful side effects of smoking tobacco, cocaine, and marijuana in terms of epithelial absorption.

Researchers are always looking for new ways to deliver therapeutic drugs to the bloodstream for distribution throughout the body. Currently, biomedical research teams are using epithelial tissue cultures to investigate a relatively new approach to drug introduction. For some time, science has known that certain compounds are easily absorbed by epithelial membranes and picked up by the blood. For example, patches of material containing drugs that inhibit motion sickness have been used by tourists on cruises. Smokers, trying to stop the nicotine withdrawal commonly associated with quitting smoking, have used nicotine patches. Patients with heart disease or burns often receive therapy by means of similar patches. Today, however, researchers are looking for wider and more varied uses of epithelial absorption as a drug delivery method.
1. a) Based on what you know of the different epithelial tissue types, which are the best candidates for this type of therapy? Explain your choices.
b) How could a clinician actually apply epithelial absorption techniques? Try to think of strategies other that the skin-patch approach.
c) Explain some of the harmful side effects of smoking tobacco, cocaine, and marijuana in terms of epithelial absorption.

CAN YOU PLEASE ANSWER 2 AND 3 :) THANK YOU

QUESTION 1 Use the information below to answer questions 1-3. Northern burrowing bugs feed on small arthropods that they search for under the bark of trees. These bugs vary considerably in the width of the pronotum; male bugs show greater variability than do females. Using light traps, you collect all of the bugs in the area, sort them by sex, and measure their pronotum width. By using a male-specific genetic markers you are able to determine which male is the father of each male offspring. The males do not associate with the females after they have mated; therefore any resemblance between males and their offspring is due only to genetics–not environment. The phenotypic variance of the males is 175.2, while the phenotypic variance of the offspring is somewhat less–146.1. The covariance in snout length between males and their offspring is 14.6. What is the heritability of pronotum width?

a) 0.083 b) 0.100 c) 0.167 d) 0.335 e) 0.500

QUESTION 2 Northern burrowing bugs shelter from cold weather in deep crevices in tree bark. Bugs who do not find shelter will not survive sever cold weather. During your study, a period of subfreezing temperatures caused all bugs that were not small enough to tunnel into crevices in the bark to die. Because of this, only those bugs with a pronotum width that averaged 12 mm narrower than the population mean to survive. Relative to the original population, how much will pronotum width differ in the next generation (young born after the severe cold period)?

a) 2.0 mm b) 3.0 mm c) 6.0 mm d) 12.0 mm e) You do not have enough data to tell

QUESTION 3 In Question 2, what type of selection is operating on pronotum width?

a) directional selection for a wider pronotum b) directional selection for a narrower pronotum c) stabilizing selection d) disruptive selection

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