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13 May 2019

b) Fully explain the genetics of this scenario, including which traits are dominant and how they produce the observed phenotypes

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Nestor RutherfordLv2

16 May 2019

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Answer the following Linked to sex genetics problems:

1.) In Drosophila the recessive mutation linked to the X chromosome, scalloped ( sd ), causes the edge of the wings to be irregular. Present the results (you must prepare the crossing scheme) phenotypic for F1 and F2 for a cross between:

A) female scallop and a normal male (regular edges)

B) A normal (homozygous) female and a scallop male .

C) Compare these results with those that would be obtained if scallop were an autosomal recessive mutation.

2.) In Drosophila the autosomal recessive ebony mutation (e) is located on chromosome 3 and produces a dark body in the fly that expresses it. What will be the phenotypic proportions for F1 and F2 that will be obtained from a cross between a scallop female and homozygous for a normal body, with an ebony male with normal wings? Solve by the bifurcated lines method.

3.) In Drosophila the recessive mutation linked to the vermilion X chromosome (v) produces bright red colored eyes in contrast to the wild phenotype that has brick red eyes. An autosomal recessive mutation, suppressor vermilion (su-v) causes homozygous or hemizygous males to females present vermilion red brick eyes. In the absence of the vermilion allele su-v has no effect on the phenotype of the eye. Determine the genotype and phenotype of F1 and F2 at a cross between a homozygous female for vermilion and su-v, with a vermilion male and wild homozygous for su-v (su-v + su-v + ) . Present the diagram of bifurcated lines for these crosses.

4.) At a crossroads with Drosophila involving recessive mutations white (linked to the X chromosome) and sepia (autosomal recessive) that produces dark eyes, predict the results of F1 and F2 when crossing pure parents with the following phenotypes.

A.) White females with sepia males.

B.) Sepia females with white males

5.) Two mothers have given birth to their children at the same time in an urban hospital with an excess of patients. The child of couple 1 has hemophilia, a condition caused by a recessive allele linked to the X chromosome. Neither parent has the condition. Couple 2 has a normal child even though the father is a hemophiliac. Several years later, couple 1 filed a lawsuit alleging that the babies were changed after birth and you are called to testify as a genetic counselor. What information would you give the jury in relation to the allegation of the couple 1?

Diagram a cross between a true breeding pea plant that produces yellow seeds (G/G) with one that produces green seeds (g/g). Carry the cross out to the F2 generation. Answer the following questions:

What was the F1 genotype and phenotype?

What kinds of gametes could the F1 individuals produce?

What were the F2 genotypes and phenotypes, and in what ratios would you expect each to occur?

Diagram a cross between a true breeding pea plant that produces round seeds and purple flowers, with one that produces wrinkled seeds and white flowers. (Round and purple are the dominant traits.) Carry the cross out to the F2 generation. Answer the following questions:

What are the P1 genotypes?

What is the F1 genotype and phenotype?

What kinds of gametes will the F1 individuals produce?

What are the F2 genotypes and phenotypes?

What genotypic and phenotypic ratios are expected in the F2 progeny?

Diagram a cross between a true breeding pea plant that produces yellow seeds (G/G) and purple flowers (W/W) with one that produces green seeds (g/g) and white flowers (w/w). Carry the cross out to the F2 generation. Answer the following questions:

What was the F1 genotype and phenotype?

What kinds of gametes could the F1 individuals produce?

What were the F2 genotypes and phenotypes, and in what ratios would you expect each to occur?

Diagram a test cross of the F1 individuals from the question above, with the homozygous recessive parent strain. What genotypes and phenotypes would you expect in the testcross progeny, and in what ratios?

If you had a fruitfly with phenotype A, what test would you make to determine if it was Aa or AA? Explain the different outcomes expected if the fly in question is AA or Aa.

If individuals of genotype AaBbCc are intercrossed:

How many different genotypes can occur in their progeny? How many different phenotypes can occur in the progeny?

orangecrow253

Shank color in chickens is determined by a single gene with two alleles, D and d. Chickens of genotype DD or Dd have white shanks, while chickens of genotype dd have yellow shanks.

Egg color in chickens is controlled by another single gene. True breeding araucana chickens (whose genotype is designated by EAEA) lay blue eggs. True breeding moron chickens (genotype EMEM) lay brown eggs. A hybrid between araucana and moron (genotype EAEM) lays green eggs.

You cross a true breeding yellow shank araucana to the true breeding white shank moron. You then cross the F1 chickens to a hybrid with yellow shanks.

Here are the results:

Phenotype	Number
Yellow shanks, lays blue eggs	110
White shanks, lays blue eggs	95
Yellow shanks, lays green eggs	206
White shanks, lays green eggs	198
Yellow shanks, lays brown eggs	94
White shanks, lays brown eggs	97

1. State your null hypothesis.

2. Perform a chi-squared analysis to test the independent assortment of these two traits.

3. What p-value does this correspond to? Do you reject or fail to reject the null hypothesis?

4. Write a brief sentence interpreting the p-value.

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