Are rare or common recessive deleterious alleles more rapidly reduced in frequency in a population via natural selection? Why?

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Nelly StrackeLv2

6 May 2018

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Which of the following is/are a plausible reason why all human populations contain lethal recessive alleles? More than one answer may be correct.

	Selection cannot "see" lethal recessive alleles when they are in heterozygotes.
	If mating is random, as the frequency of a lethal recessive allele decreases, the proportion hidden in heterozygotes increases.
	Dominant lethal alleles typically mutate quickly into recessive lethal alleles.
	When a lethal recessive allele is rare, it can be re-created by mutation as quickly as it's being removed by selection.

Mutations can sometimes add genetic diversity to populations. Explain why new mutations in somatic (body) cells are NOT a source of genetic diversity in populations.

Why might a traight (like height in humans) show continuous variation?

Explain why most RARE recessive alles in populations are deleterious (disease-causing)?

Hair color in a new breed of goats is controlled by two alleles: A and a. Goats that have genotype AA or Aa have brown hair and goats that have genotype aa have red hair. (a) If goats that have brown hair have higher fitness than goats with red hair, what will happen to the frequency of the a allele in this population? (b) will the a allele disappear completely from the population if there is negative selection on it? Why or why not? (c) Is hair color in these goats considered a polyphenism? Why or why not?

The frequency of a recessive allele at a locus with two alleles in an infinitely large population of toads is currently 0.09. There is no selection at this locus, toads mate at random, this population is completely isolated from all other populations, and no mutations are occurring at this locus.

a) What will the frequency of the recessive homozygote be in the next generation?
b) Over a long period of time, what will happen to the frequency of the recessive allele?

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Are rare or common recessive deleterious alleles more rapidly reduced in frequency in a population via natural selection? Why?

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