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No. 27 In rabbits, a series of multiple alleles controls coat color in the following way: C is dominant to all other alleles and causes full color (F). The chinchilla (CH) phenotype is due to the cch allele, which dominant to all alleles other than C. The ch allele, dominant only to ca (albino, A), results in the Himalayan (H) coat color. Thus, the order of dominance is C>cch>ch>ca for each of the following three cases, the phenotypes of the P1 generation of two crosses are shown, as well as the phenotype of one member of the F1 generation. Determine the genotypes of the P1 generation and the F1 offspring for each case, and predict the results of making each cross between F1 individuals as shown

P1 pheno.

P1 genotypes

F1 pheno.

F1 genotypes

F2 genotypes & phenotypes

(a)

H × H

→

A

×

→

F × A

→

CH

(b)

A × CH

→

A

×

→

F × A

→

F

(c)

CH × A

→

H

×

→

F × A

→

H

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30 Sep 2018

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Related questions

You are given 4 true-breeding mutant strains of fruit flies, each with a different eye colour
phenotype (apricot, orange, brown & scarlet). Specific reciprocal crosses between the recessive
mutant strains produced the following results in the F1 generations:
P1: apricot female x orange male F1 : apricot males and orange females
P1: orange female x apricot male F1 : orange males and females
P1: brown female x scarlet male F1 : wildtype males and females
P1: scarlet female x brown male F1 : wildtype males and females

i) Are the four mutant phenotypes all controlled by different alleles of a single gene? Explain.

ii) Which of the mutant phenotypes, if any, are due to allelic mutations?

iii) Which of the mutant phenotypes, if any, are due to alleles of autosomal genes? Explain.

iv) Using your own symbols for the mutations, indicate the genotypes of the F1 generation males
and females in each of the crosses.

v) Which of the F1 generations when intercrossed are likely to yield recombinant phenotypes in
the F2 generations? Explain showing the expected phenotypes and their proportions. (You
may assume that Mendel’s 2nd Law of Heredity holds true for the mutations involved in this
situation. Further assume that the double mutant results in a white eye color).

vi) Predict the outcome in the F1 generations of a reciprocal cross between a truebreeding strain
with brown eyes and another with apricot eyes.

Hi I am studying for a biology exam and I have some questionsthat are on a review sheet that i am unsure about


1. In Tomatoes, the allele for red fruit is dominant over theallele for yellow fruit. If a plant that is homozygous for redfruit is crossed with a plant with yellow fruit –

a) what is/are the genotype(s) and the phenotype(s) of the fruitproduced in the F1 generation?

b) what is/are the genotype(s) and the phenotype(s) of the fruitproduced in the F2 generation?

c) what is the phenotypic ratio of the F2 fruit?


2. A plant with red flowers is crossed with a plant with whiteflowers. All the F1 plants produced red flowers. When the F1 plantsare allowed to self-pollinate, they produce 623 plants with redflowers and 198 plants with white flowers. What are the genotypesof the P and F1 generations?

3. In Tomatoes, the allele for red fruit isdominant over the allele for yellow fruit. Theallele for tall plants is dominant of the allele forshort plants. Find the genotypes and phenotypes ofthe F1 and F2 generations and the phenotypicratio of a cross between a homozygous dominant in both genes and ahomozygous recessive in both genes. The homozygous individuals arethe Parental generation.

4. In cocker spaniels, solid coat color is dominantover spotted coat. A veterinarian has a spaniel with a solidcoat. How can she unequivocally determine the genotype of thisanimal for coat color from a single breeding?

Problem A. You cross two homozygous parents: RRYY (round yellow) and rryy (wrinkled green) to produce an F1 generation. Round seeds are dominant, yellow seeds are dominant. You cross two F1s to produce the F2 generation. In the F2 generation, you find an individual with round yellow seeds. You do a testcross to find out the genotype of this “mystery” dominant/dominant phenotype. In the offspring of the cross, you find 1?2 have round yellow seeds and 1?2 have wrinkled yellow seeds.
1. Based on these data what was the genotype of the mystery F2?

Problem B. You carry out a dihybrid cross between a red-flowered rose with long pollen grains (A1A1 LL) and a white-flowered rose with round pollen (A2A2 l l). The flower color gene (A) shows incomplete dominance, and long pollen is completely dominant to round pollen. The genes for these traits are on different chromosomes so assort independently
2. What would be the phenotypes of the F1 generation?
3. What fraction of the F2 generation is expected to have red flowers and long pollen? (As always when traits are independent, what rule can you apply to save time?)

Problem D. In the example of epistasis presented in class, the agouti allele in mice (A) codes for striped hairs and is dominant to the allele for all black hairs (a). A loss-of-function allele for the pigment gene (b) produces no pigment and is recessive to the normal, dominant allele (B). The recessive allele at b masks the effect of the A gene. A dihybrid cross of AABB and aabb is carried out.
5. Name all of the genotypes in the F2 generation that can produce an albino (no pigment) phenotype.

Problem E. A cross is made between homozygous fruit flies that differ for eye color (the st gene) and
body color (the e gene). The F1 double heterozygote is shown below using chromosome notation.
st+ e
--------------------------------------
st e+
st = the recessive allele for scarlet eyes; st+ = the dominant wildtype allele for red eyes e = the recessive allele for ebony body; e+ is the dominant wildtype allele for gray body

6. Are the chromosomes shown in the genotype above in cis or trans configuration?
7. Based on this notation, what were the genotypes and phenotypes of the two parents of the F1? (Think carefully here...)
8. With what phenotype would you cross this F1 to measure recombination frequency?

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