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In what ways are cell membranes more than simple lipid bilayers?

How does the saturation state of the hydrocarbon tail groups influence membrane fluidity?

How and why does cholesterol alter the fluidity of a membrane?

Describe evidence that supports the hypothesis that cell membranes are fluid. In what ways can membrane proteins move freely in cell membranes? How are they constrained?

(Please answer all subparts of the question, thanks so much.)

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Jamar Ferry
Jamar FerryLv2
29 Sep 2019
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Please answer the 3 following question and provide a short reasonwhy you chose your answer.
31. You observe that in certain families the segregation of atruncated deletion variant of a chromosome
correlates with developing adult onset diabetes. This observationprovides direct experimental evidence for
which of the following. (choose one answer)
A) Chromosome theory of inheritance.
B) The cell theory of life.
C) DNA constitutes the genetic material.
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32. Which of the following statements concerning membrane fluidityare correct?
A) Non-covalent interactions between lipid fatty acid tails arewhat ultimately cause the phase transition of
membranes from a fluid state to a frozen state.
B) Increased fatty acid tail length and saturation will tend todecrease membrane fluidity.
C) The presence of cholesterol in the membrane will make lipidbilayers less fluid at high temperatures.
D) The presence of cholesterol in the membrane will make lipidbilayers more fluid at low temperatures.
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F) A, B and C are correct
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33. Which of the following contribute to the asymmetric nature oflipids in the plasma membrane?
A) There is a limited set of enzymes that transfer specific lipidhead groups during lipid biosynthesis.
B) The enzymes that catalyze glycolipid synthesis are only found onthe lumen side of the ER
membrane.
C) Lipid rafts flip specific phospholipids from one leaflet of themembrane to the other.
D) The rapid diffusion of proteins in the plane of the membrane canforce lipids to jump from one side
of the membrane to the other.
E) All of the above

1) In the major biosynthetic pathway, what is the order in which mRNA moves through the various organelles?

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5) What are three different mechanisms of protein translocation? Briefly describe the state of the proteins when translocated in each of these ways.

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8) Would you expect the properties of the cisternal side of Golgi membranes to be more similar to the extracellular or cytosolic side of the plasma membrane? Why?

9) ________ are the site of cellular digestion, in which digestion occurs with the help of 50 __________. _____ digest proteins and ____ digest lipids.

10) Name two proteins you would expect to find as integral components of the RER membrane that would be absent from the SER? Name two proteins of the SER that would not be present in the RER?

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