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PLEASE HELP! Stuck on this biochem homework problem.

The lipid portion of a typical bilayer is about 30 Ã thick.

a) Calculate the minimum number of residues in an ?-helix required to span this distance.

b) Calculate the minimum number of residues in a ?-strand required to span this distance.

c) Explain why ?-helices are most commonly observed in transmembrane protein sequences when the distance from one side of a membrane to the other can be spanned by significantly fewer amino acids in a ?-strand configuration

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Casey Durgan
Casey DurganLv2
29 Sep 2019

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Related questions

2. From studies of chemistry, we know that in a straight chainhydrocarbon, such as a fatty acid, each methylene group lengthensthe chain by about 0.13 nm. From studies of protein structure, weknow that one turn of an α-helix takes 3.6 amino acid residues andlengthens the axis of the helix by about 0.56 nm. Using thisinformation, answer the following questions: (Answer parts a-c toone decimal place in units of nm, e.g. 9.0 nm.)

a. (1 pt) Using this information, how thick is the non-polarcore of the bilayer containing the GLUT1 transporter (i.e. what isthe length of each helix)?

b. (1 pt) How many fatty acid methylene groups would be neededto span this distance? (Round to closest whole number.)

c. (1 pt) Since fatty acids in membrane lipids always have aneven number of carbons in their chains, what chain lengths might becommon in this membrane? (Write the number of carbons. More thanone number may be correct.)

d. (2 pts) Most membrane lipids have 16 or 18 carbons, how canthe length of these fatty acids be accommodated in themembrane?

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